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401
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
Published 2019“…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
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402
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
Published 2022“…Nanoparticles can be used as vehicles for the localized delivery and release of DOX, decreasing the effects on neighboring healthy cells and providing more control over the drug’s release and distribution. …”
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403
Encapsulation, Release, and Cytotoxicity of Doxorubicin Loaded in Liposomes, Micelles, and Metal-Organic Frameworks: A Review
Published 2022“…Nanoparticles can be used as vehicles for the localized delivery and release of DOX, decreasing the effects on neighboring healthy cells and providing more control over the drug’s release and distribution. …”
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404
Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis
Published 2024“…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …”
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405
Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
Published 2021“…The results revealed that the new tool is beneficial, and the median times to finish the processes within the patient’s journey have significantly decreased. …”
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406
NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides
Published 1981“…The averaged TNB shifts and line-widths are indicative of 1:1 complexes whose stability is decreased by more electron-withdrawing axial halides or phenyl substituents, consistent with the porphyrin acting as a π donor in the adduct. …”
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407
The effects of a change in the point system on immigration
Published 2016“…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …”
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408
Unsustainability in emergent systems
Published 2017“…These challenges are already significant enough to seriously hamper the network's ability to deliver an acceptable level of service within reasonable norms for environmental, health and safety impacts, especially in and around the country's major urban centers. …”
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409
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
Published 2022“…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …”
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410
Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
Published 1991“…Decreased striatal dopamine levels in these latter rat strains were associated with increased dopamine turnover. …”
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411
miRNA-dependent regulation of STIM1 expression in breast cancer
Published 2019“…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …”
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412
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413
Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study
Published 2019“…We also calculated the reorientational correlation time of the water molecules, and we found that the rotational motion of confined water inside the membrane is anisotropic and the reorientational correlation time of confined water is slower than that of bulk water. …”
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414
Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System
Published 2017“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
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415
Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology
Published 2023“…Features of transmission line maintenance were used to increase accuracy of estimation. …”
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416
An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing
Published 2023“…<p dir="ltr">The significant effect of the dressing process on the surface of the grinding wheel (GW) and the need to provide an optimal dressing condition are the requirements of reduction machining time and energy consumption in the sustainable grinding process. …”
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417
Enhanced oil recovery using hyperbranched polyglycerol polymer-coated silica nanoparticles
Published 2021“…A D<sub>PSiMNPs</sub> = 100 mg/L was sufficient to achieve %η<sub>dem</sub> of 99.4% for C<sub>oil</sub> = 100 mg/L and slightly decreased to ~93% for C<sub>oil</sub> ~4000 mg/L. The PSiMNPs can be reused up to 15 times with a steady %η<sub>dem</sub> of 89.1% for C<sub>oil</sub> = 100 mg/L and 88.6% for C<sub>oil</sub> = 4000 mg/L. …”
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418
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (p < 0.05). …”
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419
The effect of the local inertial term on the fluid flow in channels partially filled with porous material
Published 2001“…Also, it is found that the deviation between the predictions of the transient and the quasi-steady models is more significant in the porous domain and the deviation decreases as the time proceeds.…”
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420
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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