Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma by Shebaby, W.

“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Social Media Use and Body Checking Among Lebanese Adults by Korkomaz, Aya

“…That being said, interventions regulating social media content to limit the spread of unrealistic beauty standards and media literacy campaigns educating people may be helpful to decrease body checking behaviors thus decreasing the risk of body image dissatisfaction and disordered eating.…”
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Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters by Lina Majed (7485380)

“…<div>Walking is the most accessible and common type of physical activity. Exercising at one’s self-selected intensity could provide long-term benefits as compared to following prescribed intensities. …”

Managing Endothelial Dysfunction in COVID-19 by Matli, Kamal

“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention by Almonzer Al-Qiami (22393303)

“…No statistically significant difference in mean arterial pressure was observed between the two groups (MD -5.15, 95% CI [-10.38 to 0.08 mmHg], <i>P</i> = 0.09). …”

Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

A potential therapeutic agent for sickle cell anaemia by Nature Research (16552612)

“…They also found increased levels of ROS that were associated with decreased levels of antioxidant enzymes and their co-factors.…”

Protein Glycation in Plants—An Under-Researched Field with Much Still to Discover by Naila Rabbani (291722)

“…Further research to decrease protein glycation in plants may lead to improved plant growth and assist the breeding of plant varieties resistant to environmental stress and senescence—including plants of commercial ornamental and crop cultivation value.…”

Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Gowtham Kumar Subbaraj (17807615)

“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”

Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort by Ashraf T. Hantouly (14150319)

“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”

Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition by Bouclaous, Carmel

“…All groups showed a decrease in relative intestinal absorption with time. …”
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Glycemic Index of commonly consumed Lebanese mixed meals and desserts by Daher, C. F.

“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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A Numerical Study of Heat Transfer and Fluid Flow in a Channel with an Array of Pin Fins in Aligned and Staggered Configurations by Issa, Johnny

“…Fin array configurations with large spacing ratio, S*, showed a better performance than smaller spacing ones. For fin arrays with a large row number in the streamwise direction, the best performance was obtained in the case corresponding to the aligned configuration with the large spacing ratio, S* = 1.…”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden by Monika, Rawat

“…One bryophyte species (Dicranum elongatum) among the six most commonly found decreased with proximity to the trail. …”
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The role of job description as a motivational tool. (c2000) by Nahfawi, Ghina

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Improving pediatric trauma care: an automated system for wrist trauma detection using GELAN by Promit Basak (22997776)

“…The results of our study highlight the capacity of deep learning to improve the diagnosis of pediatric trauma, decrease the burden on radiologists, and boost patient outcomes.…”

BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”