Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro حسب Najem, Sonia A.

"…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides حسب Kabbani, Ahmad T.

"…The averaged TNB shifts and line-widths are indicative of 1:1 complexes whose stability is decreased by more electron-withdrawing axial halides or phenyl substituents, consistent with the porphyrin acting as a π donor in the adduct. …"
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The effects of a change in the point system on immigration حسب Chemin, Matthieu

"…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …"
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Optimization of Vapor Compression Refrigeration Cycles with Clathrate Hydrates Thermal Energy Storage حسب Gadalla, Akram Mohamed

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Receivers location privacy in avionic crowdsourced networks: Issues and countermeasures حسب Savio Sciancalepore (16864152)

"…Therefore, taking into account these considerations, the data provided by a few antennas in one of the most popular crowdsourcing platforms, Opensky Network, are released removing any information that could lead to their direct location identification.…"

Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy حسب Khoury, Reine

"…The results reveal the potential therapeutic benefits of plasma factors released in response to exercise in an autophagy dependent manner.…"
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3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction حسب Masoud Forsat (14158980)

"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment حسب Farhat, Peter

"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
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Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties حسب Al Zaabi, Alanood

"…Soot particles, released during diesel combustion, adversely affect human health and the environment. …"
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miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"

α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain حسب Eid, Fady

"…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…"
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Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System حسب Bair, Scott

"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
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Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms حسب ALBLOOSHI, ROUDHA KHALID ABDULLA

"…This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …"
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Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology حسب Senyuk, Mihail

"…Features of transmission line maintenance were used to increase accuracy of estimation. …"
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon حسب Mokhbat, Jacques M.

"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells حسب Castellino, R.C.

"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation حسب Sleiman, Sama F.

"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"

Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19 حسب Abu Saleh Md Moin (6189512)

"…Basal M1 macrophage activation was characterized by elevated levels of M1 macrophage-specific surface proteins, CD80 and CD38, and cytokines or chemokines (CXCL1, CXCL5, RANTES) released by activated M1 macrophages. Two potent M1 macrophage activation markers, CXCL9 and CXCL10, were decreased in OT2D. …"