Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders by Jaunetta Hill (18255631)

“…Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …”

Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 by Sarah Naja (9954737)

“…</p><h3>Limitations</h3><p dir="ltr">There is no recognized optimal cut-off point to distinguish ‘high risk’ in pregnancy-related anxiety scales.</p><h3>Conclusions</h3><p dir="ltr">Pregnancy-related anxiety is more prevalent than generalized anxiety among pregnant women in Qatar, indicating that stakeholders must include screening for pregnancy-related anxiety in Qatar's clinical guidelines. …”

Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19 by Abu Saleh Md Moin (6189512)

“…Two potent M1 macrophage activation markers, CXCL9 and CXCL10, were decreased in OT2D. Activated M2 macrophages were characterized by elevated levels of plasma CD163, TFGβ-1, MMP7 and MMP9 in OT2D. …”

Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study by Abduljaleel Abdullatif Zainel (18055382)

“…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …”

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample by Menatalla Mekhaimar (14103708)

“…In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

“…<p dir="ltr">Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. …”

Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes by Ahmad Salman (3173418)

“…We, therefore, aimed to determine the sociodemographic, health-related behavior and clinical factors associated with meeting the recommended levels of physical activity in Scottish adults with diabetes. …”

Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Jaimie D Steinmetz (18015919)

“…We estimated the prevalence and relative contribution of avoidable causes of blindness and vision impairment globally from 1990 to 2020. …”

The Gulf Cooperation Council states: Crystallization of the regional cooperation and alliances amid dwindling resources by Evren Tok (14779270)

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage by Florence Hariton (18629764)

“…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …”

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …”

Influence of direct electric field on PMCG-alginate-based microcapsule by Peter Kasak (1360617)

Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial by Peter Oesch (3572426)

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…We modelled multiple smoking-related indicators from 3625 nationally representative surveys. …”

Impact of Work-Life Balance on Female Employee Motivation by Haleema Raja (22196926)

Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors by Yu Wang (12152)

“…</p><p dir="ltr">Aerosol phase state is dependent on relative humidity (RH) and chemical composition (key factors determining aerosol water uptake). …”

Assessment Tools for Pulmonary Involvement in Patients with Ankylosing Spondylitis: Is Diaphragmatic Ultrasonography Correlated to Spirometry? by Rim Dhahri (21406871)

“…The left inspiratory diaphragmatic thickness was correlated with the percentage of the FVC decrease (r= 0.35; <i>p</i> = 0.01) defined as the percentage of difference between FVC and supine FVC. …”

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Muhanad Alhujaily (11630107)

“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”

Central and peripheral muscle fatigue following repeated‐sprint running in moderate and severe hypoxia by Nathan Townsend (14779642)

“…No significant differences between conditions for mean distance occurred in set 2. There was a decrease in maximal voluntary contraction torque (Δ = −31.4 ± 18.0 N m, <i>P</i> < 0.001) and voluntary activation (%VA; Δ = −7.1 ± 5.1%, <i>P</i> = 0.001) from Pre- to Post-set 1, but there was no effect of hypoxia. …”