-
61
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
Get full text
Get full text
Get full text
article -
62
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
Get full text
Get full text
Get full text
masterThesis -
63
-
64
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …”
-
65
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
Published 2020“…In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. Our results show a decrease in the migratory rate of the cells and their rate in wound closure. …”
Get full text
Get full text
Get full text
masterThesis -
66
Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
Get full text
Get full text
Get full text
masterThesis -
67
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
-
68
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…These mega-projects may include the construction of major buildings, roads, railway lines and airports. The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. …”
Get full text
-
69
Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules
Published 2020“…The nanocapsules exhibited a >30–fold decrease in IC50, suggesting enhanced anticancer activity associated with curcumin encapsulation. …”
Get full text
Get full text
Get full text
Get full text
article -
70
Nurses’ work environment and intent to leave in Lebanese hospitals
Published 2011“…Results The NWI-R subscale with the lowest mean score related to control. Younger nurses had lower scores on organizational support and career development. …”
Get full text
Get full text
Get full text
article -
71
The Antioxidant and Pro-apoptotic effects of Sternbergia clusiana Bulb Ethanolic Extract on Breast Cancer Cells in vitro
Published 2021“…MDA-MB-231 cells treated with SbBEE exhibited morphological and biochemical hallmarks of apoptosis that were detected through DNA fragmentation, the hyper-expression of phosphatidylserine on the outer leaflet of cells membrane and the upregulation of proteins able to mediate cell death through apoptosis (c-PARP, Bax/ Bcl2). The prominent decrease in ROS levels upon treatment confirmed the antioxidant property of the extract being investigated, highlighting the promising effect of SbBEE in breast cancer treatment.…”
Get full text
Get full text
Get full text
masterThesis -
72
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
Get full text
Get full text
Get full text
article -
73
Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
Published 2023“…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …”
Get full text
Get full text
Get full text
article -
74
Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
Published 2023“…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …”
-
75
Effect of consanguinity on birth weight for gestational age in a developing country
Published 2007“…Consanguinity, the marriage between relatives, has been associated with adverse child health outcomes because it increases homozygosity of recessive alleles. …”
Get full text
Get full text
Get full text
Get full text
article -
76
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…Addition of N-acetyl-cysteine (NAC); being a reactive oxygen species (ROS) scavenger, led to a significant decrease in the cytotoxicity of arginine deprivation to U251 and A172 cells, indicating that ROS generation reversed the cytotoxicity of arginine deprivation to GBM cells. …”
Get full text
Get full text
Get full text
masterThesis -
77
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
Published 2021“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”
-
78
Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy
Published 2021“…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …”
-
79
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
Published 2017“…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …”
Get full text
Get full text
Get full text
article -
80
Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes
Published 2023“…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …”