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441
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
منشور في 2022"…They further establish the SOCE hypomorph line as a genetic model to define the therapeutic window of SOCE inhibition and dissect toxicities associated with chronic SOCE inhibition in a tissue-specific fashion.…"
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442
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
منشور في 2025"…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…"
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443
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
منشور في 2025"…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …"
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444
A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems
منشور في 2020"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"
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445
Total Quality Implementation on Marine Transportation Association Under Natural Disruption of COVID-19 Pandemic
منشور في 2021"…The total lockdown or partial lockdown devised by countries all over the world, which means that most economic activities were postponed until the outbreak, is contained. …"
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446
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
منشور في 2024"…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …"
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447
COVID-19 may have increased global support for universal health coverage: multi-country observational study
منشور في 2023"…It also examined which psychological factors related to the socioeconomic interdependence exposed by the pandemic may be associated with a potential change.…"
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448
Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden
منشور في 2002"…The increase in norfloxacin and ciprofloxacin resistance started relatively simultaneously in all hospitals, around 1991. …"
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article -
449
A component analysis of positive behaviour support plans
منشور في 2012"…Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. No single intervention component was found to have a greater association with reductions in challenging behaviour…"
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article -
450
Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis
منشور في 2024"…Average weekly working hours decreased from 59.2 hours in Phase 1 to 49.8 hours in Phase II. …"
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masterThesis -
451
Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
منشور في 2016"…Increasing complexity appeared to lead to decreasing beetle widths. 9 beetle species were relatively rare in, or absent from, the higher complexity treatments, including 5 of the 6 largest species. 2 rare, small beetle species were only found in higher complexity treatments. …"
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article -
452
Crystallization properties of arsenic doped GST alloys
منشور في 2019"…Optical band gap (E<sub>opt</sub>) values of the as-deposited films show a clear increasing trend; 0.6 eV for GST to 0.76 eV for (GST)<sub>0.85</sub>As<sub>0.15</sub>. The decreases in E<sub>opt</sub> for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …"
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453
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"
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454
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …"
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455
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"
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456
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
منشور في 2022"…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…"
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457
Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
منشور في 2022"…The overall SPE-related mortality rate was 8 % (95 % CI: 5.26–10.96). …"
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458
Essays on the effect of excess compensation and governance changes on firm value
منشور في 2012"…Our results suggest that an increase in director excess compensation decreases the likelihood of CEO turnover, reduces the turnover-performance sensitivity, and increases managerial entrenchment. …"
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masterThesis -
459
Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
منشور في 2023"…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…"
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460
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
منشور في 2022"…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …"