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141
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …"
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masterThesis -
142
1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
منشور في 2010"…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …"
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article -
143
Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells
منشور في 2015"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the 4 cell lines. …"
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article -
144
The antioxidant and anticancer effects of Wild Carrot oil extract
منشور في 2012"…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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article -
145
The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013)
منشور في 2013"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. …"
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masterThesis -
146
Cryomyolysis, a new procedure for the conservative treatment of uterine fibroids
منشور في 1998"…Normal uterine volume ranged from 35.6 to 548.7 ml preoperatively and 45.1 to 729.6 ml postoperatively (mean increase 40%); however, myoma volume showed a mean decrease of 6% (range-87-28%). …"
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article -
147
Crisis Communication Management Model in the Public Sector of Dubai
منشور في 2012"…The unexpected events occur every day, and with the increase of the negative outcomes of these incidents on people and organizations, they would become crises that require effective management. …"
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148
Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
منشور في 2021"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"
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149
Sequential therapy in patients receiving Fluoroquinolones at the American University of Beirut Medical Center. (c2001)
منشور في 2001"…Date of switch (if applicable), oral antibiotic chosen, mean time to switch, mean hospital duration, and mean treatment duration were also recorded. …"
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masterThesis -
150
Buckling Analysis of Functionally Graded Materials (FGM) Thin Plates with Various Circular Cutout Arrangements
منشور في 2022"…The normalized buckling load was also calculated to compare the buckling performance of FGM plates with various dimensions. Moreover, von Mises stress analysis was examined to understand the yield capability of the FGM plates in addition to the buckling modes that show the stress distribution of the critical buckling stress. …"
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article -
151
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
منشور في 2021"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
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masterThesis -
152
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …"
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article -
153
Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
منشور في 2023"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"
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154
Rescue cerclage
منشور في 2006"…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …"
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article -
155
Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
منشور في 2019"…The quantification of mental states was performed by means of statistical analysis of indexes based on GTA, behavioral responses of time-on-task (TOT), and Brunel Mood Scale (BRMUS). …"
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article -
156
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157
Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion
منشور في 2016"…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …"
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article -
158
The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
منشور في 2013"…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …"
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article -
159
Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
منشور في 2020"…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
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masterThesis -
160
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
منشور في 2020"…</p><h3>Results</h3><p dir="ltr">Treatment of human breast cancer cells with increasing concentrations of VCX caused a significant decrease in cells growth and proliferation. …"