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Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death
Published 2024“…Inhibition of autophagy decreased sensitivity to arginase-induced cytotoxicity in all cell lines, and hence reversed cell death. …”
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Efficient experimental design for uncertainty reduction in gene regulatory networks
Published 2015“…The experimental design method utilizes the concept of mean objective cost of uncertainty (MOCU). MOCU quantifies the expected increase of cost resulting from uncertainty. …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”
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Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…Gene expression in cell clusters was determined by RT-PCR. Data are mean ± SEM (n=6)</p> <p>Results: Flow cytometry data for relevant stage-specific markers showed 96 % OCT4 positive, 89% SOX17 and 83% PDX1 positive cells, indicating good pluripotency, high definite endoderm and pancreatic progenitor induction, respectively. …”
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Experimental Verification of Low-Pressure Kinetics Model for Direct Synthesis of Dimethyl Carbonate Over CeO<sub>2</sub> Catalyst
Published 2024“…The kinetic model predictions closely aligned with experimental data, demonstrating a 17% mean absolute percentage error and indicating a high level of predictability. …”
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The Use of Microwave Tomography in Bone Healing Monitoring
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Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
Published 2020“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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30
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …”
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Short-Term Load Forecasting in Active Distribution Networks Using Forgetting Factor Adaptive Extended Kalman Filter
Published 2023“…The forgetting factor improves the estimation accuracy and increases the system convergence when compared with the AEKF. …”
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
Published 2010“…The mean Qmax increased from 10.6±3.3 mL/sec at screening to 13.6±6.7 mL/sec at 12-months following treatment. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…By contrast, mean blood pressure might have increased in east and southeast Asia, south Asia, Oceania, and sub-Saharan Africa. …”
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition
Published 2025“…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …”
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masterThesis -
38
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
Published 2019“…Addition of excess L-citrulline rescued only one of three cell lines tested, indicating that the majority of cell lines are completely auxotrophic for arginine. …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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masterThesis