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Bevacizumab and neovascular age related macular degeneration
Published 2011“…We reviewed articles between 1997 and January 2010 that included at least 30 patients with AMD who received intravitreal bevacizumab monotherapy for at least 1 year. The mean number of letters gained, decrease in CRT, and number of injections were 8 letters, 125.3 µm, and 4.3 injections, respectively. …”
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122
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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124
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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125
High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry
Published 2025“…Developing advanced sensing technologies capable of real-time, sensitive detection of acetic acid is crucial for addressing analytical challenges and meeting the growing demand for efficient monitoring solutions across various industries. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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127
Effect of climate change on the annual energy consumption of a single family house in British Columbia
Published 2018“…This paper investigates the effect of climate change on the energy consumption of a single-family house with different energy efficiency levels, i.e. bylaw to meet current National Energy Code of Canada for Buildings (NECB), and passive house (PH) to meet the PH requirements under four climate zones in British Columbia, Canada. …”
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128
Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells
Published 2023“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”
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Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort
Published 2023“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”
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Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Specifically, we show that vocabulary divergence increases over time, as expected. Due to such significant vocabulary change in Turkish over time, similarity between the periods 1920–1929 and 2010–2019 is 57%. …”
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131
Development and Mechanical Performance of Sustainable Geopolymer Concrete
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132
Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy...
Published 2019“…Males demonstrated a significant decrease in anxiety scores compared to females. Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…”
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133
Glycemic Index of commonly consumed Lebanese mixed meals and desserts
Published 2010“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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Improving pediatric trauma care: an automated system for wrist trauma detection using GELAN
Published 2025“…The results of our study highlight the capacity of deep learning to improve the diagnosis of pediatric trauma, decrease the burden on radiologists, and boost patient outcomes.…”
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A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media
Published 2024“…However, when accounting for leaching, which was significant in some organic media but expected to decrease with time, most organic media (SCG, date seeds, coco coir and bone) achieved around 80 % TOC removal. …”
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Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts
Published 2022“…The mean Hibbs angle decreased from 153.07 to 142.32° (MD = 10.54°, p < 0.001). …”
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
Published 2020“…In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. Our results show a decrease in the migratory rate of the cells and their rate in wound closure. …”
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Recent advances in the treatment and outcome of locally advanced rectal cancer
Published 1999“…No significant differences were seen in patients (age, gender, race) or tumor characteristics (mean distance from the anal verge, annularity, fixation). …”
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