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181
Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria
Published 2024“…Notably, SSA and South Asia are the regions most lagging behind the Sustainable Development Goal (SDG) 3.2, aiming for <12 neonatal deaths per 1,000 live births by 2030. Within SSA, Nigeria, the most populous country, records the highest number of neonatal deaths annually. …”
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182
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
Published 2020“…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …”
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183
Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Findings: In 2021, the global stillbirth rate was 23·0 (95% uncertainty interval [UI] 19·7–27·2) per 1000 births (stillbirths plus livebirths) at 20 weeks' gestation or longer, compared to 16·1 (13·9–19·0) per 1000 births at 28 weeks' gestation or longer. …”
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184
Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar
Published 2024“…</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …”
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185
Recent advances in the treatment and outcome of locally advanced rectal cancer
Published 1999“…No significant differences were seen in patients (age, gender, race) or tumor characteristics (mean distance from the anal verge, annularity, fixation). …”
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186
Renal Function Decline in Recipients and Donors of Kidney Grafts
Published 2015“…Results: Decline in renal function was estimated at 1-year post-transplantation and annually thereafter (median follow-up 8 years, range 3.6-18.3), as the mean of the annualized decrease in the glomerular filtration rate. …”
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187
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
Published 2015“…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …”
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188
Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of...
Published 2021“…Age-standardised death rate decreased by 15.7% (8.6 to 21.0), during the period 1990–2019. …”
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189
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …”
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190
Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex
Published 2019“…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …”
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191
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Published 2022“…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …”
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192
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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193
Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water
Published 2022“…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …”
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194
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
Published 2024“…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …”
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195
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
Published 2025“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”
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196
YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
Published 2025“…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …”
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197
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Published 2024“…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …”
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198
Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
Published 2024“…All blends show an increase in brake mean effective pressure (BMEP) compared to B0, with the maximum enhancement observed in B10 with an average increase of 13% across all speeds. …”
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199
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …”
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200
Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
Published 2020“…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …”
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