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301
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase
منشور في 2022"…Moreover, dex stimulates spherogenesis of both cell lines, which is mediated by TDO, evident by its suppression with 680C91, a TDO inhibitor. …"
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302
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
منشور في 2023احصل على النص الكامل
doctoralThesis -
303
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304
Post-materialistic values and entrepreneurial intention– the case of Saudi Arabia
منشور في 2018"…An online survey returned 405 valid questionnaires, representing a 27 per cent response rate. The data were analysed using partial least structural equation modelling. …"
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305
Writing and publishing language studies in the Arab region [Khitabaat Journal]
منشور في 2024"…Klein starts from an implicit assumption that writing and reading are individual activities and suggests that (individual) writers must decrease their production to enable their (individual) readers to read it. …"
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306
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307
Grid electricity demand reduction through applying passive and active strategies for a house in Baghdad, Iraq
منشور في 2013"…By adopting 1Pearl, it provided 4.33% energy reduction while 2 Pearls can achieve about 4.37% decrease in energy. This means that roof insulation should take priority when considering the passive solutions for conserving energy. …"
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308
Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
منشور في 2018"…Therefore, the key challenge is to reduce the consumption of fossil fuels which decreases the production of greenhouse gases such as CO2 and CH4 by using renewable energy technologies to provide clean carbon free energy that can combat future energy security challenges. …"
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309
Differential water quality in confined and free-flowing water bodies, Lebanon
منشور في 2003"…This emphasises the importance of assessing surface water quality as a projected means to increase water availability. This study involves two different water bodies, the freely flowing Nahr-Ibrahin River and the Qaraaoun Reservoir, an impoundment of the Litani River. …"
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article -
310
Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
منشور في 2019"…The quantification of mental states was performed by means of statistical analysis of indexes based on GTA, behavioral responses of time-on-task (TOT), and Brunel Mood Scale (BRMUS). …"
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article -
311
Testing and Evaluation of a Smart Irrigation System towards Smart landscaping in UAE
منشور في 2017"…The outcomes of the use of SMS have shown a better results in water conservation and a decrease in water flow in the month of September by 21% and 26% in October. …"
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312
A framework for implementing Green Supply Chain Management: The Case of Petco Gulf
منشور في 2021"…From this research, it was found that as Petco gulf is present in the U.A.E. it can take advantage of this and by applying the GSCM strategies against each of its components this will help the company by, increased overall gross profit with the decrease in cost since going green in its supply chain means reducing the overheads. …"
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313
A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells
منشور في 2008"…Results WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against melanoma cell line A375, B16 and B16EGFRvIII, respectively. WP1066 suppressed the phosphorylation of JAK2 and STAT3 (Tyr705) in these cells. …"
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article -
314
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
منشور في 2008"…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …"
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article -
315
Tumor protease-activated fusion toxins
منشور في 2003"…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …"
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masterThesis -
316
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
منشور في 2025"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"
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317
Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3
منشور في 2023"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"
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318
Inositol 1,4,5-Trisphosphate Receptors in Hypertension
منشور في 2018"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca<sup>2+</sup> signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP<sub>3</sub>R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"
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319
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
منشور في 2021"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"
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320
Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
منشور في 2023"…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …"