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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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102
Managing Endothelial Dysfunction in COVID-19
Published 2022“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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103
The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention
Published 2025“…No statistically significant difference in mean arterial pressure was observed between the two groups (MD -5.15, 95% CI [-10.38 to 0.08 mmHg], <i>P</i> = 0.09). …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma
Published 2012“…Finally, we detected an increase in p-ERK in StarD13 knockdown cells, uncovering a potential link between Rho GTPases and ERK activation.…”
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107
COVID-19 and Anemia: What Do We Know So Far?
Published 2023“…The primary effect of these mechanisms is a decrease in circulating hemoglobin levels, reducing oxygen availability for cells. …”
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Adsorption in nanopores with finite pore walls from truncated graphene
Published 2011“…This model mimics real carbon samples better than usually used infinite pore models, whatever is the assumed pore shape (slit-like, tubular, curved etc). In particular, it allows us to account for the adsorption at the pore edges, totally neglected in infinite models. …”
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110
Evaluation of the Surface Integrity and Recast Layer in Electrical Discharge Turning of WC-Co Composites
Published 2024“…<div><p>Tungsten carbide (WC) and its composites are typically associated with high hardness and high wear resistance, posing challenges in conventional machining processes like turning. To address the machining difficulties of WC-Co, electrical discharge turning (EDT) was proposed. …”
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111
The effects of blockchain implementation on Cyber risks mitigating strategies in the financial sector in the United Arab Emirates
Published 2018“…The statistical package for social sciences (SPSS) was used to analyze the responses by using different analysis techniques like Cronbach’s alpha, correlation test and regression test. …”
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112
Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort
Published 2023“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”
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Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice
Published 2025“…It has been suggested that sucrose consumption attenuates stress-induced cortisol secretion, whereas aspartame has been reported to increase activity of glucocorticoids and anxiety-like behavior in rodents Aim: The present study aimed to assess the differential effects of sucrose and aspartame on the physiological and behavioral response in chronic stress in mice. …”
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Exploring the potential of applying Sustainable Retrofitting Policies & Regulations for existing low-rise small-scale Residential Buildings (Villas) in Dubai, UAE
Published 2020“…Green retrofit for existing buildings has now become as one of the effective options to decrease energy consumption worldwide. It is crucial to develop sustainable retrofitting policies and regulations for the existing old villas since there is lack of regulations to retrofit old existing low scale residential buildings like villas in Dubai. …”
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115
Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
Published 2003“…All groups showed a decrease in relative intestinal absorption with time. …”
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Glycemic Index of commonly consumed Lebanese mixed meals and desserts
Published 2010“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
Published 2017“…Here, we investigated the effects of exendin-4 or selenium administration on the expression of glucagon-like peptide-1 receptor (GLP-1R), insulin receptor substrate-1 (IRS-1), and preproinsulin in the pancreas of diabetic rats. …”
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Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar
Published 2024“…SSIs with multiple drug-resistant organisms were significantly high. Physicians should give special attention to modifiable risk factors and antibiotic stewardship to decrease the risk of SSI and improve patient outcomes.…”
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Clinical characteristics and treatment outcomes of coats disease in a Saudi Arabian population
Published 2015“…Conclusion: Although rare, Coats disease is usually advanced at presentation and has a poor visual prognosis in the Saudi population, like in other populations. The findings of this study give validity and applicability to the Shields staging scheme, which we recommend using in clinical practice.…”
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Slater to Mott Crossover in the Metal to Insulator Transition of Nd2Ir2O7
Published 2016“…Upon cooling below the transition temperature, this compound exhibits a gap opening with an energy shift of quasiparticle peaks like a band gap insulator. The quasiparticle peaks are strongly suppressed, however, with further decrease of temperature, and eventually vanish at the lowest temperature, leaving a nondispersive flat band lacking long-lived electrons. …”
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