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421
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
منشور في 2025"…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …"
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422
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
منشور في 2024"…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …"
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423
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
منشور في 2020"…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …"
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article -
424
Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition
منشور في 2025"…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …"
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masterThesis -
425
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
منشور في 2021"…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …"
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masterThesis -
426
Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
منشور في 2022"…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …"
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427
Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers
منشور في 2015"…The folate receptor is widely expressed on the surface of several cell lines and tumors; including ovarian, brain, kidney, breast, and lung cancers. …"
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article -
428
Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells
منشور في 2020"…We showed that short exposure of multiple hPSC lines (hESCs/hiPSCs) to 10 μM RA dramatically enhances embryoid body (EB) formation through regulation of genes activating signaling pathways associated with cell proliferation, survival and adhesion, among others. …"
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429
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430
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
منشور في 2019"…Low-grade chronic inflammation of adipose tissue may link PCOS and adverse CVR. In pro-inflammatory states such as PCOS, spontaneous activation of the alternative pathway of complement results in increased generation of acylation stimulating protein (ASP) from adipocytes irrespective of body mass index.…"
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431
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making
منشور في 2019"…Results Study participants who were invited and completed the survey were 657. The percentage mean score of participants’ attitudes and concern was 70.1 ± 16.4 and 58.3 ± 15.3 respectively. …"
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article -
432
Rapid mercury removal using living indigenous microalgal communities for water treatment applications
منشور في 2025"…Comprehensive isotherm analysis revealed the Dubinin-Radushkevich model provided the best fit (R<sup>2</sup> = 0.998), indicating physical adsorption as the predominant mechanism, as the calculated mean free energy (E = 5.00 kJ/mol) falls within the 1–8 kJ/mol range characteristic of physical adsorption. …"
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433
Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity
منشور في 2013"…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …"
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article -
434
Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
منشور في 2011"…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …"
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article -
435
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436
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
منشور في 2019"…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m<sup>2</sup>) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …"
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437
SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES
منشور في 2020"…The applied adjusting risks are comprising three value levels. Minimum, mean, and maximum cost risks. Simulated costs under adjusting risks' levels can be presented in the same exported data sheet. …"
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438
PSA-activated proaerolysin as a prostate specific cancer therapy
منشور في 2006"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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conferenceObject -
439
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
منشور في 2021"…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …"
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440
Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
منشور في 2025"…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …"