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361
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”
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362
Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar
Published 2024“…The total economic benefit of the ASP maturity was calculated as the sum of the cost savings and the cost avoidance associated with the service minus the operational cost.3 Cost savings were the reduction in therapy cost linked to decreased antimicrobial consumption and resource utilization. …”
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363
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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364
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
Published 2013“…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…”
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365
Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation
Published 2008“…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …”
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366
PSA-activated proaerolysin as a prostate specific cancer therapy
Published 2006“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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367
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
Published 2016“…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …”
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masterThesis -
368
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
Published 2024“…F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …”
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369
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
Published 2017“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”
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370
Work-life balance, perceived stress, & locus of control
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371
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
Published 2025“…While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …”
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372
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …”
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373
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…<div><p>Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. …”
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374
Associating learning technology to sustain the environment through green mobile applications
Published 2019“…Thus, it presents a stepping stone towards linking learning technology while at the same time sustaining the environment.…”
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375
Performance Analysis of FSO Communications With Diversity Methods
Published 2016“…By comparing the MIMO and cooperative methods with point receivers, we reach the central result that it is always better, from a diversity gain point of view, to add more apertures to the source and destination rather than adding more relays in their vicinity despite the fact that the fading variance along FSO links decreases with the distance. For receivers that implement aperture averaging, we derive conditions under which MIMO techniques are unconditionally better than cooperative techniques with any network topology.…”
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376
Fracture Behavior of ASTM A633 steel plate specimens with edge crack at tensile test
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conferenceObject -
377
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”
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378
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379
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
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380
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
Published 2018“…EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to several malignancies including PTLDs, which are one of the most common malignancies following transplantation. …”