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Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion
Published 2016“…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …”
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84
The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …”
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85
Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
Published 2014“…Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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87
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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Notes total mesorectal excision (TME) for patients with rectal neoplasia
Published 2014“…This approach may lead to reduced postoperative pain, decreased hernia formation and improved cosmesis when compared to standard laparoscopy. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit. …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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92
Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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93
Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge
Published 2023“…The main issue found relating to the two extruder production lines productivity was where availability and quality show a significant decrease. …”
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Percutaneous Aspiration Irrigation Drainage Technique in the Management of Septic Arthritis in Children
Published 2011“…Result: Apyrexia was obtained after a mean period of 2 days. The mean draining duration was 4.5 days. …”
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Investigation of an integrated hydrogen production system based on nuclear and renewable energy sources: a new approach for sustainable hydrogen production via copper-chlorine ther...
Published 2011“…Thermochemical water splitting with a copper–chlorine (Cu–Cl) cycle could be linked with nuclear and renewable energy sources to decompose water into its constituents, oxygen and hydrogen, through intermediate Cu and Cl compounds. …”
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96
Exercise-induced Citrate Enhances Associative Memory Formation by Modulating Histone Acetylation in a Sex-dependent manner
Published 2023“…In fact, we found that citrate-dependent enhancement of learning and memory is linked to an increase in hippocampal histone acetylation, specifically acetylation of histone H4. …”
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97
Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample
Published 2015“…Conclusion: The current study adds to the body of literature about ED by identifying the major factors that are linked to ED vulnerability in female young adults. …”
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98
The Antioxidant and Pro-apoptotic effects of Sternbergia clusiana Bulb Ethanolic Extract on Breast Cancer Cells in vitro
Published 2021“…MDA-MB-231 cells treated with SbBEE exhibited morphological and biochemical hallmarks of apoptosis that were detected through DNA fragmentation, the hyper-expression of phosphatidylserine on the outer leaflet of cells membrane and the upregulation of proteins able to mediate cell death through apoptosis (c-PARP, Bax/ Bcl2). The prominent decrease in ROS levels upon treatment confirmed the antioxidant property of the extract being investigated, highlighting the promising effect of SbBEE in breast cancer treatment.…”
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99
Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators
Published 2017“…Responses on Likert scales were converted to percentage mean scores. Results: The overall percentage mean scores ± standard deviation of knowledge was 59 ± 17, perception towards clinical nurse coordinators (79 ± 14) and attitude towards seeking their services (69 ± 16). …”
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100
Investigation of an integrated hydrogen production system based on nuclear and renewable energy sources: a new approach for sustainable hydrogen production via copper–chlorine ther...
Published 2011“…Thermochemical water splitting with a copper–chlorine (Cu–Cl) cycle could be linked with nuclear and renewable energy sources to decompose water into its constituents, oxygen and hydrogen, through intermediate Cu and Cl compounds. …”
Get full text
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