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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
منشور في 2024"…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy...
منشور في 2019"…Males demonstrated a significant decrease in anxiety scores compared to females. Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…"
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43
Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31
منشور في 2020"…RT-qPCR assays revealed that LRRK2 transcripts were dramatically reduced in our microdeletion patient DGDP289A compared to his healthy grandfather with no deletion. The decreased expression of LRRK2 may affect protein–protein interactions between LRRK2 and its binding partners, of which eight have previously been linked to intellectual disability. …"
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44
Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …"
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45
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…Together, the combined burden accounted for by URIs and otitis media in 2021 was 6·86 million (4·24 to 10·4) years lived with disability and 8·16 million (4·99 to 12·0) disability-adjusted life-years (DALYs) for all ages across males and females. …"
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46
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47
Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…DALYs were estimated as the aggregation of the years of life lost (YLLs) due to premature mortality and years lived with disability (YLDs). …"
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48
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …"
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49
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A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor
منشور في 2022"…Co-expression of the sensors with M<sup>pro</sup> in live cells resulted in their cleavage while mutation of the critical C145 residue (C145A) in M<sup>pro</sup> completely abrogated their cleavage. …"
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51
Circular economy application for a Green Stadium construction towards sustainable FIFA world cup Qatar 2022™
منشور في 2021"…Therefore, sustainable construction became a hot topic, which strives to reduce material consumption, limit constructional waste disposal, and decrease contribution to climate change. In line with Qatar's commitment to organizing a sustainable FIFA World Cup in 2022, this study aims to conduct an environmental life cycle assessment (LCA) for the construction of the Education City Stadium. …"
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52
Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
منشور في 2023"…In this study, we investigate tradeoffs between improved fuel economy and rebound effects from a life-cycle perspective. Our results show that autonomy introduces an average 21.2% decrease in operation phase emissions due to improved fuel economy while manufacturing phase emissions can surge up to 40%. …"
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53
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
منشور في 2020"…Methods Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017, we estimated the prevalence, morbidity, and mortality attributable to chronic respiratory diseases through an analysis of deaths, disability-adjusted life-years (DALYs), and years of life lost (YLL) by GBD super-region, from 1990 to 2017, stratified by age and sex. …"
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54
The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
منشور في 2020"…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …"
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55
Deep Learning for Dynamic Wildlife Monitoring: A Real-Time Approach
منشور في 2025"…The parameters of the fine-tuned YOLOv11 decreased by 30% relative to the previous version, resulting in a very small model size of 5.5 MB and reduced processing time. …"
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56
The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017
منشور في 2020"…We report on the incidence, mortality, and disability-adjusted life-years (DALYs) due to stomach cancer in 195 countries and territories from 21 regions between 1990 and 2017. …"
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57
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
منشور في 2020"…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …"
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Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats
منشور في 2023"…Thus, CBD has the potential to decrease HbA1C in diabetic patients (Diabetes Mellitus type 1) and improve their lives. …"
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Renal Function Decline in Recipients and Donors of Kidney Grafts
منشور في 2015"…Results: Decline in renal function was estimated at 1-year post-transplantation and annually thereafter (median follow-up 8 years, range 3.6-18.3), as the mean of the annualized decrease in the glomerular filtration rate. …"
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Cost-effectiveness of novel treatment of hepatitis C virus in Lebanese patients
منشور في 2018"…Outcomes of early treatment with DAAs upon HCV diagnosis led to an incremental cost of 27,268 euro per QALY gained at first year of treatment, and of 1527 euro per additional life-year extended. Sensitivity analysis showed that a 25% decrease in the cost of dual drug option resulted in a decrease of incremental cost to 16,982 euro per QALY gained at first year of treatment with DAAs upon early HCV diagnosis. …"
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