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361
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. Despite RFX6’s known function in islet development, its specific role in diabetes pathogenesis remains unclear. …"
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362
Energy Performance of Earth Sheltered Spaces in Hot-Arid Regions
منشور في 2011"…Earth sheltered spaces represent the long-gone pattern of living and sheltering against dangerous and harsh environment. …"
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363
Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
منشور في 2022"…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …"
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364
Gold-Conjugated Curcumin as a Novel Therapeutic Agent against Brain-Eating Amoebae
منشور في 2020"…Balamuthia mandrillaris and Naegleria fowleri are free-living amoebae that cause infection of the central nervous system, granulomatous amoebic encephalitis (GAE) and primary amoebic meningoencephalitis (PAM), respectively. …"
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365
Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up
منشور في 2022"…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …"
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366
10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes
منشور في 2020"…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"
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367
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
منشور في 2025"…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …"
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368
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
منشور في 2024"…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …"
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369
Total and segmental liver volume variations
منشور في 2015"…Indeed, improvement in outcome and decrease in complications after extended hepatic resections of increasing complexity have been linked to preservation of adequate functional parenchyma.17 There are few studies in the literature describing the relative contributions of the anatomic hepatic segments to the TLV. …"
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370
Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers
منشور في 2020"…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …"
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371
History of WOFAPS (1963–2019)
منشور في 2020"…This vision was unique at the time and foreshadowed the major increase in advocacy activity which has emerged in recent years. …"
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372
Cigarette use among Arab Americans in the Detroit metropolitan area
منشور في 1992"…With the growing numbers of Middle Eastern immigrants, there is potential for a dramatic increase in smoking-related health problems.…"
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373
Milk Other Than Breast Milk and the Development of Asthma in Children 3 Years of Age. A Birth Cohort Study (2006–2011)
منشور في 2018"…A sample of 1121 children was extracted from the Environments for Healthy Living longitudinal birth cohort study. Introduction of MOTBM during the first six months after birth increased almost two-fold the risk of development of persistent asthma after adjusting for other covariates (Adjusted Relative Risk (ARR): 1.71, 95% CI: 1.03–2.83, p = 0.038). …"
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374
Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of...
منشور في 2021"…Cabo Verde had the highest increase in age-standardised incidence (284.2% (214.1 to 362.8)) and death rates (190.3% (139.3 to 251.1)) between 1990 and 2019. …"
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375
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
منشور في 2019"…Low-grade chronic inflammation of adipose tissue may link PCOS and adverse CVR. In pro-inflammatory states such as PCOS, spontaneous activation of the alternative pathway of complement results in increased generation of acylation stimulating protein (ASP) from adipocytes irrespective of body mass index.…"
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376
Effect of COVID-19 on the Generation of Waste in Marrakech, Morocco
منشور في 2021"…<h3>Background</h3><p dir="ltr">The production of solid waste continues to increase as the population and standard of living increases. …"
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377
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making
منشور في 2019"…Results Study participants who were invited and completed the survey were 657. The percentage mean score of participants’ attitudes and concern was 70.1 ± 16.4 and 58.3 ± 15.3 respectively. …"
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378
Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…Its heightened risk calls for increased cancer awareness, preventive measures, affordable early-stage detection, and cost-effective therapeutics in Asia. …"
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379
Basal and Stress-Induced Network Activity in the Adrenal Medulla In Vivo
منشور في 2022"…Hypoglycemic stress, induced by insulin administration resulted in increased activity of a subset of the chromaffin cells. …"
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380
The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome
منشور في 2021"…This cohort reported that the clinical reproductive outcomes of intracytoplasmic sperm injection showed no statistical significance with increase sperm DNA fragmentation levels. In sperm DNA fragmentation above 30%, favourable females had significantly higher clinical pregnancy rate and live birth rate than unfavourable females, while fertilisation rate and miscarriage rate showed no significance between the subgroups. …"