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321
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
منشور في 2020"…However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic agents against breast cancer need investigation.</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …"
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322
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
منشور في 2024"…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …"
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323
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
منشور في 2013"…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …"
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324
The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar...
منشور في 2023"…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …"
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325
Synergetic effects of dodecylamine-functionalized graphene oxide nanoparticles on antifouling and antibacterial properties of polysulfone ultrafiltration membranes
منشور في 2021"…All membranes were characterized in terms of chemical structure, morphology, hydrophilicity, porosity and mean pore size. Cross-section SEM images showed the distribution of GO and rGO-DDA between the pores and on the polymer walls. …"
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326
The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
منشور في 2022"…In this single-centre, cumulative, prospective, registry study, 321 hypogonadal men (mean age: 58.9 years) received testosterone undecanoate injections in 12-week intervals for up to 12 years. …"
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327
Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
منشور في 2023"…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …"
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328
Using Data Mining and Text Mining Techniques in Predicting the Price of Real Estate Properties in Dubai
منشور في 2014"…It is found that the results of linear regression prediction have been improved significantly after adding text mining to the experiments. The root mean squared errors RMSEs for all data subsets have decreased leading to enhancing the accuracy of prediction. …"
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329
The chemical analysis of Lebanese olive oil and the influence of oil enriched diet on Plasma Lipid profile in rats. (c2002)
منشور في 2002"…In order to observe difference in lipid profile, well designed dietary experiments in humans is needed, because the squalene metabolism in rats is different than in humans.…"
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masterThesis -
330
Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial
منشور في 2023"…Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …"
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331
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…These findings contribute to the growing understanding of nanoparticle toxicity profile and underscore the need for further research to ensure the safe application of nanoparticles in biomedical and other fields.…"
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332
Coping mechanisms among Lebanese first-time college students
منشور في 2012"…Implications for Nursing Practice and Research: The results of this study will provide a better understanding of factors that are predictive of decreased well-being in Lebanese first-time college students and will be valuable in developing culturally sensitive intervention of stress and coping management program with a surveillance system and a systematic planning and evaluation procedure to respond to emerging and changing students’ needs at the Lebanese American University.…"
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masterThesis -
333
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. Despite RFX6’s known function in islet development, its specific role in diabetes pathogenesis remains unclear. …"
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334
Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
منشور في 2022"…Our results illustrated that the increasing levels of Cd in the sand, significantly (P < 0.05) decreased shoot length, root length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight, germination percentage, germination index, mean germination time, time to 50% germination, chlorophyll a, chlorophyll b, total chlorophyll and carotenoid contents in all genotypes of B. oleracea. …"
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335
An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat...
منشور في 2022"…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …"
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masterThesis -
336
Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
منشور في 2021"…Moreover, daylighting analysis shows decreased average illuminance levels from 407.8 to 154.97 Lux, equivalent to a 60% reduction in December and June. …"
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337
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…In order to control fine particles transport in porous media, the behavior itself needs to be predicted and analyzed. Which could be quite costly to do in a laboratory experiment, hence the modelling of such a behavior would be an optimum way to study. …"
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338
Immunoprofile of childhood diabetes
منشور في 2023"…Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…"
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339
Business Continuity Management Maturity Model for Banks in UAE
منشور في 2008"…They are faced with increasing levels of global competition, demanding customers and employees, shrinking product lifecycles and decreasing acceptable response times (Lockamy & McCormack, 2004) They have employees and deal with clients, suppliers & vendors from all over the world. …"
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340
Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up
منشور في 2022"…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …"