Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells حسب Ejlal Abu-El-Rub (5168183)

"…Based on its importance for cancer cells, we aim to investigate the molecular mechanisms that link HSP90 inhibition in colon cancer cells with oxidative stress and mitochondrial stress—related regulators.…"

Exploring beyond numeric weight loss: The metabolic effects of semaglutide حسب Sara Sokary (17337724)

"…</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …"

Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. We also concluded that autophagy was activated in response to arginine depletion and plays a protective role at early time points. …"
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) حسب Khalil, Nathalie

"…We have established that autophagy, a process of cellular destruction activated in response to arginine deprivation, can be the leading cause of cell death at late drug incubation times. Hence, our study demonstrates that HuArgI (Co)-PEG5000 is a novel, potent and selective potential therapeutic approach for PC.…"
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Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Hedyeh Ebrahimi (7321358)

"…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …"

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties حسب Ovidiu, Ciobanu

"…ObjectiveThe aim of this study is to investigate how hydrogen peroxide (HP) treatments affect enamel porosity and protein structure, as well as their impact on tooth shade and hardness over time. MethodsFifty healthy teeth were collected from adult patients. …"
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Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: a prospective cohort analysis حسب Ashraf Gad (17040114)

"…PW correlated with IVSs (p=0.019), while the longest placental diameter was linked to a decrease in LV internal dimension during diastole (LVIDd) (estimate=−0.07, p=0.039), LV mass (estimate=−0.11, p=0.024), and LV mass/volume (estimate=−0.55, p=0.005).…"

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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Supplementation of retrobulbar block with clonidine in vitreoretinal surgery حسب Abi Nader, Elie

"…Conclusions The addition of clonidine 0.5 μg/kg to the local anesthetics of a retrobulbar block for vitreoretinal surgery decreases the frequency of postoperative pain and prolongs the time of analgesia.…"
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Raising awareness among health educators and educational institutions of the need to overcome the language barrier among Non-Native English speaking students of Health Sciences in... حسب Ghizlane Bendriss (9025832)

"…This study showed a decrease in 2014 for the proportion of students in the foundation year that studied sciences in English with 73% in 2013 to 39% in 2014. …"

Influence of co-current vapor flow on falling film over horizontal tube حسب Furqan Tahir (14429547)

"…First, the liquid load is varied between 0.02 and 0.05 kg/(m·s), and its effects on the film thickness and the wetting time are calculated, presented and discussed. Afterwards, the impact of co-current vapor flow on film distribution, wetting time, minimum thickness and its location are quantified and examined by increasing the vapor velocity up to 6 m/s with 2 m/s intervals. …"

Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics حسب Farah F. Salameh (21797300)

"…The impact of various parameters on MB removal was assessed, including solution pH, adsorbent dosage, pollutant concentration, and contact time. Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …"

Self-Organization and Multi-Agent Reinforcement Learning for Taxi Dispatch حسب Alshamsi Omran, Aamena Ali Ahmed

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Throughput of ARQ protocols over Rician, Nakagami and MIMO block fading channels حسب Zummo, Salam A.

"…Keywords: ARQ, throughput, error probability, fading channels, space-time, multiple antennas, transmit diversity, MIMO, Rician, Nakagami.…"
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Fixed-interval versus OCT-guided variable dosing of intravitreal bevacizumab in the management of neovascular age-related macular degeneration حسب El-Mollayess, Georges M.

"…Results Compared to baseline, variable dosing had a mean improvement in BCVA of 11.0 letters after 12 months vs 9.2 letters for fixed-interval dosing (P = .81). …"
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Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity حسب Mohamed Abu-Farha (18535590)

"…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …"

The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar... حسب Muna Abed Alah (18171346)

"…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …"

Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar حسب Suhaila Ghuloum (796180)

"…</p> <h3>Results</h3> <p>A total of 406 nurses and 92 doctors participated in the study. The nurses' mean MICA score was significantly higher than that of the physicians. …"

Synergetic effects of dodecylamine-functionalized graphene oxide nanoparticles on antifouling and antibacterial properties of polysulfone ultrafiltration membranes حسب Abedalkader Alkhouzaam (15842647)

"…All membranes were characterized in terms of chemical structure, morphology, hydrophilicity, porosity and mean pore size. Cross-section SEM images showed the distribution of GO and rGO-DDA between the pores and on the polymer walls. …"

Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting حسب Ananth Nazarene (21239912)

"…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …"