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441
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Based on its importance for cancer cells, we aim to investigate the molecular mechanisms that link HSP90 inhibition in colon cancer cells with oxidative stress and mitochondrial stress—related regulators.…”
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442
Throughput of ARQ protocols over Rician, Nakagami and MIMO block fading channels
Published 2020“…Keywords: ARQ, throughput, error probability, fading channels, space-time, multiple antennas, transmit diversity, MIMO, Rician, Nakagami.…”
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443
Influence of co-current vapor flow on falling film over horizontal tube
Published 2021“…First, the liquid load is varied between 0.02 and 0.05 kg/(m·s), and its effects on the film thickness and the wetting time are calculated, presented and discussed. Afterwards, the impact of co-current vapor flow on film distribution, wetting time, minimum thickness and its location are quantified and examined by increasing the vapor velocity up to 6 m/s with 2 m/s intervals. …”
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444
Sustainable Detoxification of Methylene Blue in Wastewater via Tea Residue Adsorption: Optimization and Kinetics
Published 2025“…The impact of various parameters on MB removal was assessed, including solution pH, adsorbent dosage, pollutant concentration, and contact time. Optimal conditions were identified as pH 10, a dosage of 4 g/L, a concentration of 100 mg/L, and a contact time of 2 h, achieving nearly 99% removal efficiency at 25 °C. …”
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445
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446
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
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447
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…We have established that autophagy, a process of cellular destruction activated in response to arginine deprivation, can be the leading cause of cell death at late drug incubation times. Hence, our study demonstrates that HuArgI (Co)-PEG5000 is a novel, potent and selective potential therapeutic approach for PC.…”
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448
Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: a prospective cohort analysis
Published 2024“…PW correlated with IVSs (p=0.019), while the longest placental diameter was linked to a decrease in LV internal dimension during diastole (LVIDd) (estimate=−0.07, p=0.039), LV mass (estimate=−0.11, p=0.024), and LV mass/volume (estimate=−0.55, p=0.005).…”
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449
Raising awareness among health educators and educational institutions of the need to overcome the language barrier among Non-Native English speaking students of Health Sciences in...
Published 2015“…This study showed a decrease in 2014 for the proportion of students in the foundation year that studied sciences in English with 73% in 2013 to 39% in 2014. …”
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450
Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis
Published 2025“…</p><h3>Results</h3><p dir="ltr">Six studies, five observational and one randomized (n = 553 patients, out of which 45.7% received advanced therapy), were included in our meta‐analysis. …”
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451
Fixed-interval versus OCT-guided variable dosing of intravitreal bevacizumab in the management of neovascular age-related macular degeneration
Published 2012“…Results Compared to baseline, variable dosing had a mean improvement in BCVA of 11.0 letters after 12 months vs 9.2 letters for fixed-interval dosing (P = .81). …”
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452
The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar...
Published 2023“…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …”
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453
Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar
Published 2022“…</p> <h3>Results</h3> <p>A total of 406 nurses and 92 doctors participated in the study. The nurses' mean MICA score was significantly higher than that of the physicians. …”
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454
Synergetic effects of dodecylamine-functionalized graphene oxide nanoparticles on antifouling and antibacterial properties of polysulfone ultrafiltration membranes
Published 2021“…All membranes were characterized in terms of chemical structure, morphology, hydrophilicity, porosity and mean pore size. Cross-section SEM images showed the distribution of GO and rGO-DDA between the pores and on the polymer walls. …”
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455
Evaluating the impact of the Minimization of Aggression and Violence (MoAV) intervention on mechanical restraint use in Qatar's acute mental health setting
Published 2025“…The percentage of restrained patients decreased from 25 % to 4 %, p = (<0.001). The mean duration of restraint incidents slightly increased from 59.1 min in 2016 to 61.3 min in 2021, though this change was not statistically significant. …”
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456
Using Data Mining and Text Mining Techniques in Predicting the Price of Real Estate Properties in Dubai
Published 2014“…It is found that the results of linear regression prediction have been improved significantly after adding text mining to the experiments. The root mean squared errors RMSEs for all data subsets have decreased leading to enhancing the accuracy of prediction. …”
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457
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …”
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458
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…<h3>Objective</h3><p dir="ltr">The aim of this study is to investigate how hydrogen peroxide (HP) treatments affect enamel porosity and protein structure, as well as their impact on tooth shade and hardness over time. </p><h3>Methods</h3><p dir="ltr">Fifty healthy teeth were collected from adult patients. …”
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459
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. Despite RFX6’s known function in islet development, its specific role in diabetes pathogenesis remains unclear. …”
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460
Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index
Published 2021“…In addition, coagulation variables such as thrombin-activatable fibrinolysis inhibitor, plasminogen activator inhibitor-1 (PAI-1), D-dimer, Antithrombin and thrombomodulin have been reported to be elevated in PCOS compared to control subjects, and the functional coagulation tests including prothrombin time, thrombin time and fibrin degradation products may be predictive of PCOS. …”