eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”

Optical coherence tomography findings in autoimmune retinopathy by Abazzari, Azin

“…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …”
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”

Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats by Barakat, Ghinwa

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Reducing terrorism with development ; the United Nations' new path. (c2009) by Kassis, Maria-Rita

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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

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A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV by Rizk, Sandra

“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
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Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

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Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma by Abdalla, Eddie

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Detecting attacks in a cluster based QOS-OLSR protocol. (c2014) by Sanadiki, Hiba

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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

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A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter by Ahmad Khan (6067526)

“…This SSC is often considered as the main DC nanogrid energy control unit that is linking the nanogrid with the main utility AC grid and managing the nanogrid elements. …”

DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations by El Maarri, Osman

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10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes by Goran Petrovski (129836)

“…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …”

Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities by Saade, S.

“…The estimated total phenolic content was 228.5 GAE per gram. The results show that Lycopus uniflorus possesses a potential anti-inflammatory, anti-ulcerogenic and antioxidant activities.…”
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Crunching the numbers of food poisoning in Qatar by Nature Research (16552612)

“…</p><p>The incidence rate of salmonellosis in Qatar in 2012 was 18.1 per 100,000. This rate is comparable to others in countries such as Canada (19.4/100,000), Poland (22.9/100,000) and the US (16.4/100,000).…”

Shear performance of FRP Reinforced Deep Beams Made of Ultra High Performance Concrete (UHPC) by Salman, Omar

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Orofacial Clefts by El Baba, Nada

“…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …”
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Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows by Tohid, Adibi

“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study by Mona Metwally El-Sayed (17725127)

“…Older adult participants were selected to undergo eight sessions over four weeks. The Geriatric Anxiety Scale and Arabic Scale of Happiness were used to evaluate the participants' anxiety and happiness levels.…”