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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…MG activated the intrinsic pathway of apoptosis, with decrease of mitochondrial and spliceosomal proteins. …”
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Efficient experimental design for uncertainty reduction in gene regulatory networks
Published 2015“…The experimental design method utilizes the concept of mean objective cost of uncertainty (MOCU). MOCU quantifies the expected increase of cost resulting from uncertainty. …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”
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An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
Published 2020“…HCT STEM majors’ graduates showed no significant differences from AY 2010 to the AY 2017; the latter shows that although STEM enrolments have increased in HCT, graduates of STEM are consistent and unchanged, meaning that somewhere during their tertiary education, students are not continuing their studies in STEM majors. …”
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The Photocatalytic Degradation of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in the Presence of Silver–Titanium Based Catalysts
Published 2020“…Byproducts of degradation were evaluated using Gas chromatography/mass spectrometry (GC–MS), resulting in 2,3,7-trichlorodibenzo-p-dioxin, a lower chlorinated congener and less toxic, as the main degradation product. Enzyme Linked Immunosorbent Assay (ELISA) was used to evaluate the relative toxicity of the degradation byproducts were a decrease in optical density indicated that some products of degradation could be potentially more toxic than the parent TCDD. …”
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Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…Gene expression in cell clusters was determined by RT-PCR. Data are mean ± SEM (n=6)</p> <p>Results: Flow cytometry data for relevant stage-specific markers showed 96 % OCT4 positive, 89% SOX17 and 83% PDX1 positive cells, indicating good pluripotency, high definite endoderm and pancreatic progenitor induction, respectively. …”
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Experimental Verification of Low-Pressure Kinetics Model for Direct Synthesis of Dimethyl Carbonate Over CeO<sub>2</sub> Catalyst
Published 2024“…The kinetic model predictions closely aligned with experimental data, demonstrating a 17% mean absolute percentage error and indicating a high level of predictability. …”
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Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31
Published 2020“…RT-qPCR assays revealed that LRRK2 transcripts were dramatically reduced in our microdeletion patient DGDP289A compared to his healthy grandfather with no deletion. The decreased expression of LRRK2 may affect protein–protein interactions between LRRK2 and its binding partners, of which eight have previously been linked to intellectual disability. …”
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The Use of Microwave Tomography in Bone Healing Monitoring
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Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
Published 2020“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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Short-Term Load Forecasting in Active Distribution Networks Using Forgetting Factor Adaptive Extended Kalman Filter
Published 2023“…The forgetting factor improves the estimation accuracy and increases the system convergence when compared with the AEKF. …”
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
Published 2010“…The mean Qmax increased from 10.6±3.3 mL/sec at screening to 13.6±6.7 mL/sec at 12-months following treatment. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…By contrast, mean blood pressure might have increased in east and southeast Asia, south Asia, Oceania, and sub-Saharan Africa. …”
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Predictors of Disordered Eating in Young Males
Published 2017“…Therefore, the latter pathway was removed from the model. The link between media pressure, strategies to decrease body weight and emotional eating was partially mediated by depressive symptomatology. …”
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