eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways حسب Zvi Cramer (10742876)

"…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …"

Coping strategies, optimism, and resilience factors associated with mental health outcomes among medical residents exposed to coronavirus disease 2019 in Qatar حسب Malek Smida (14777104)

"…Strategies promoting optimism, resilience, and approach coping styles can decrease the mental health burden of the pandemic on medical residents.…"

Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization حسب Adrián Martín‐Segura (18615133)

"…In recent studies, we reported that the mild and gradual loss of cholesterol in the synaptic fraction of hippocampal neurons during aging leads to a decrease in synaptic plasticity evoked by glutamate receptor activation and also by receptor tyrosine kinase (RTK) signaling. …"

Crumpled MXene nanosheets for sensing of ascorbic acid in food, biological fluids, and erythrocytes in-vitro microenvironment حسب Shabi Abbas Zaidi (4234354)

"…The sensor also demonstrated excellent reproducibility (~1 % RSD for five repetitive assays) and a shelf life of nearly one month with a negligible decrease in response. …"

Building A Passive Thermal Management System Using Phase Change Material Embedded In Porous Media حسب Azzam, Mohammed H. A.

احصل على النص الكامل

Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene حسب Ammouri, A.H.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"

Total hip arthroplasty: Evolution of the use of dual mobility cups in Lebanon حسب Assi, Chahine

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats حسب Barakat, Ghinwa

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk حسب Merhi, Mahmoud

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai حسب HAJI, HASSAN

"…It is true that the aim of any business is to make profit, with decreased profit in the sector many entrepreneurs have discovered other investment schemes which has resulted to more demand of the workforce. …"
احصل على النص الكامل

A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV حسب Rizk, Sandra

"…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Breast cancer cells and bone marrow mesenchymal stromal cells حسب Faour, Wissam H.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma حسب Abdalla, Eddie

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Detecting attacks in a cluster based QOS-OLSR protocol. (c2014) حسب Sanadiki, Hiba

احصل على النص الكامل
احصل على النص الكامل

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells حسب Castellino, R.C.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows حسب Tohid, Adibi

"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Orofacial Clefts حسب El Baba, Nada

"…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Role of family in supporting children with mental disorders in Qatar حسب Abdulnaser A. Fakhrou (16855155)

"…In addition, the study will examine the importance of family rehabilitation and integration of people with mental disorders into society.</p><h3>Methods</h3><p dir="ltr">The study adopts the descriptive-analytical method and uses a questionnaire to gather data from the participants. …"

Carotid artery revascularization through a radiated field حسب Lesèche, Guy

"…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل