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541
Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans
Published 2024“…More recently, mutations in the tryptophanyl-tRNA synthetase 1 (WARS1) have been linked to various human diseases, from intellectual disability to various types of cancer. …”
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542
Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
Published 2019“…These interpretive cognitive acts of meaning construction by leaders and followers include significant elements of conceptual thinking and explanation. …”
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543
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”
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544
Prescription errors with chemotherapy
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545
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546
Implementation of corporate governance rules and procedures in lebanese firms
Published 2014“…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …”
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547
An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat...
Published 2022“…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …”
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masterThesis -
548
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th...
Published 2020“…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change −0·2% [95% UI −1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). …”
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549
Elemental distributions in the marine sediments off Doha, Qatar: role of urbanisation and coastal dynamics
Published 2024“…Decadal variability is evident in element concentrations, which are linked to the urbanisation of the capital city in the State of Qatar. …”
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550
Collaborative hierarchical caching and transcoding in edge network with CE-D2D communication
Published 2020“…However, the high load in peak hours consumes the limited available bandwidth of existing cellular and backhaul links leading to low network performance. Hence, an elastic system model is required to maintain the high Quality of Experience (QoE) as the resource demands increase. …”
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551
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552
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553
Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development
Published 2024“…We found that female mice exposed to PFOS alone showed an increase in weight, while HFD expectedly increased body weight. …”
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554
The Effects of Social Determinants of Health on Cardiovascular Outcomes in Lebanese with Type 2 Diabetes
Published 2020“…Background: Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases in Lebanon and is known to increase the risks of cardio-metabolic events. Diabetes self-management is essential for glycemic control and prevention of cardiovascular complications. …”
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masterThesis -
555
Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts ROLE IN SUPPRESSION OF c/EBP/NF-κB-MEDIATED MEKK...
Published 2006“…Cyclooxygenase-2 (COX-2) overexpression has been linked to cell survival, transformation, and hyperproliferation. …”
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556
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…Proteins susceptible to MG modification were enriched in protein folding, protein synthesis, serine/threonine kinase signalling, glycolysis and gluconeogenesis. MG was increased in high glucose by increased flux of MG formation linked to increased glucose metabolism mediated by proteolytic stabilisation and increase of hexokinase-2 (HK-2); later potentiated by proteolytic down regulation of glyoxalase 1 (Glo1) - the major enzyme of MG metabolism. …”
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557
The Potential of Lettuce Seed Assay for Sustainable Applied Toxicity Testing
Published 2025“…<p dir="ltr">This study was conducted to establish an approach for environmental toxicity assessment by using Effect-Directed Analysis (EDA) to increase the chances of toxicant identification through links between toxicity testing and chemical analysis. …”
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558
The Association Between Estrogen‐Containing Oral Contraceptive Pills and Hypothyroidism
Published 2025“…These findings highlight the need for further research to explore the mechanisms linking OCP use to thyroid dysfunction and to investigate other potential risk factors.…”
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559
Integration of Smart Sensors in Buildings to achieve Energy Efficiency in Hot and Humid Climate
Published 2021“…It is also estimated that this utilization would grow to above 50% by 2030 because of the fast and consistent growth in economic activity and increase in population around the world. People tend to spend the greater part of their time in indoor spaces e.g., commercial and residential buildings. …”
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560