PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”

Prescription errors with chemotherapy by Saad, Aline

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Thermodynamic Analysis of an Integrated Hydrogen Production System Based on Solar and Nuclear Energy Sources in the UAE by Babu, Binish Sam

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Implementation of corporate governance rules and procedures in lebanese firms by Elgammal, Walid

“…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …”
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An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

“…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …”
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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Jaimie D Steinmetz (18015919)

“…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global crude prevalence of avoidable vision impairment and blindness in adults aged 50 years and older did not change between 2010 and 2019 (percentage change −0·2% [95% UI −1·5 to 1·0]; 2019 prevalence 9·58 cases per 1000 people [95% IU 8·51 to 10·8], 2010 prevalence 96·0 cases per 1000 people [86·0 to 107·0]). …”

Elemental distributions in the marine sediments off Doha, Qatar: role of urbanisation and coastal dynamics by Varis Mohammed Hasna (22046888)

“…Decadal variability is evident in element concentrations, which are linked to the urbanisation of the capital city in the State of Qatar. …”

Collaborative hierarchical caching and transcoding in edge network with CE-D2D communication by Emna Baccour (16896366)

“…However, the high load in peak hours consumes the limited available bandwidth of existing cellular and backhaul links leading to low network performance. Hence, an elastic system model is required to maintain the high Quality of Experience (QoE) as the resource demands increase. …”

Collaborative Caching for D2D Content Sharing in 5G by Abdelsalam, Ansam Elfadil Kamel

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Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development by Issam Hmila (9239059)

“…We found that female mice exposed to PFOS alone showed an increase in weight, while HFD expectedly increased body weight. …”

The Effects of Social Determinants of Health on Cardiovascular Outcomes in Lebanese with Type 2 Diabetes by Saadé, Rita

“…Background: Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic diseases in Lebanon and is known to increase the risks of cardio-metabolic events. Diabetes self-management is essential for glycemic control and prevention of cardiovascular complications. …”
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Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts ROLE IN SUPPRESSION OF c/EBP/NF-κB-MEDIATED MEKK... by Faour, Wissam

“…Cyclooxygenase-2 (COX-2) overexpression has been linked to cell survival, transformation, and hyperproliferation. …”
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Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…Proteins susceptible to MG modification were enriched in protein folding, protein synthesis, serine/threonine kinase signalling, glycolysis and gluconeogenesis. MG was increased in high glucose by increased flux of MG formation linked to increased glucose metabolism mediated by proteolytic stabilisation and increase of hexokinase-2 (HK-2); later potentiated by proteolytic down regulation of glyoxalase 1 (Glo1) - the major enzyme of MG metabolism. …”

The Potential of Lettuce Seed Assay for Sustainable Applied Toxicity Testing by Ammar M. S. Abdalla (23752962)

“…<p dir="ltr">This study was conducted to establish an approach for environmental toxicity assessment by using Effect-Directed Analysis (EDA) to increase the chances of toxicant identification through links between toxicity testing and chemical analysis. …”

The Association Between Estrogen‐Containing Oral Contraceptive Pills and Hypothyroidism by Lama Alkahlout (22392196)

“…These findings highlight the need for further research to explore the mechanisms linking OCP use to thyroid dysfunction and to investigate other potential risk factors.…”

Integration of Smart Sensors in Buildings to achieve Energy Efficiency in Hot and Humid Climate by JABR, BILAL SUDQI SAEED

“…It is also estimated that this utilization would grow to above 50% by 2030 because of the fast and consistent growth in economic activity and increase in population around the world. People tend to spend the greater part of their time in indoor spaces e.g., commercial and residential buildings. …”
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Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Joseph L Ward (9715619)

“…Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. …”

The Islamist groups in Tripoli. (c2008) by Abbas, Nivine H.

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RFX3 is essential for the generation of functional human pancreatic islets from stem cells by Bushra Memon (4792767)

“…</p><h3>Data availability</h3><p dir="ltr">The RNA-seq datasets have been submitted to the Zenodo repository and can be accessed via the following links: DOI https://doi.org/10.5281/zenodo.13647651 (PPs); and DOI https://doi.org/10.5281/zenodo.13762055 (SC-islets).…”

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

“…InterpretationOver the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. …”
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