PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Structural Hole Theory, Audit Committee Member Gender, and Financial Restatements by Radaideh, Farah Ghazi

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Managing Endothelial Dysfunction in COVID-19 by Matli, Kamal

“…Secondary outcomes included the composite outcome of ICU admission or the need for mechanical ventilation, all-cause mortality, and the occurrence of side effects Results Of 42 randomized patients, 37 were included in the primary analysis. The mean age of the patients was 57 years; the mean BMI of study participants was 29.14. …”
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The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention by Almonzer Al-Qiami (22393303)

“…No statistically significant difference in mean arterial pressure was observed between the two groups (MD -5.15, 95% CI [-10.38 to 0.08 mmHg], <i>P</i> = 0.09). …”

Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome by Hammad Shabir Chaudhry (20376378)

“…</p><h3>Outcomes</h3><p dir="ltr">The patient was asymptomatic on her follow-up visit after 1 week of discharge and tolerated chemotherapy well. Her liver enzymes (Alkaline phosphatase, Alanine aminotransferase, Aspartate aminotransferase had decreased significantly.…”

Effect of dietary protein level on gentamicininduced nephrotoxicity in rats and on the circadian rhythms of food ingestion by Zeeni, Nadine

“…In a second study, rats were fed the same diets, however, the treatment given was a sham injection. Results suggest that chronic gentamicin treatment leads to a decrease in food intake and flattening of the rhythms of food ingestion. …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

Effectiveness of external myofascial mobilisation in the management of male chronic pelvic pain of muscle spastic type: A retrospective study by M. S Ajimsha (21250760)

“…The mean (SD) NIH-CPSI score at initial evaluation was 29.41 (8.3) and decreased to 9.14 (3.45) after the fifth visit. …”

Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery by Staples, Bryant J.

“…Initially, concentrations were highest in heart and liver, but within 24 h they decreased significantly. …”
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Anti-angiogenic effect of nano-formulated water soluble kaempferol and combretastatin in an in vivo chick chorioallantoic membrane model and HUVEC cells by Gowtham Kumar Subbaraj (17807615)

“…Morphometric analysis of CAM showed that treatment with nano-formulated water-soluble kaempferol and combretastatin caused a substantial decrease in density, vessel network, branch points, and nets of CAM blood vessels. …”

Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort by Ashraf T. Hantouly (14150319)

“…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…”

Sex differences on quality of life and mental health outcomes when using a brief cognitive-behavioral skill building intervention with adolescent Syrian refugees: a secondary analy... by Kazandjian, Chant

“…Males demonstrated a significant decrease in anxiety scores compared to females. Among males only, significant decreases in depression and anxiety scores were observed with significant improvement in total QOL.…”
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Glycemic Index of commonly consumed Lebanese mixed meals and desserts by Daher, C. F.

“…The determination of the Glycemic Index (GI) and Load (GL) for mixed meals serves as a dietetic tool in meal planning to reinforce the benefits of low GI meals and decrease the physiological effects of high GI meals. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up by Wahiba Elhag (5245547)

“…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …”

The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France by Harakeh, Mostafa

“…Accordingly, we find that, following IFRS adoption, earnings management activities decrease among high-divergence firms prior to issuing SEOs. …”
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Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice by Akil, Shaymaa

“…Method: Female C57BL/6J mice (n > 275, aged 8–10 weeks) were given plain water, 12.3% sucrose, or 0.03% aspartame for two weeks, then half of each group underwent a 3-week chronic variable stress (CVS) protocol using mild unpredictable stressors. …”
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A cooperative watchdog model based on Dempster–Shafer for detecting misbehaving vehicles by Abdel Wahab, Omar

“…As a solution, we propose a two-phase model that is able to motivate nodes to behave cooperatively during clusters’ formation and detect misbehaving nodes after clusters are formed. Incentives are given in the form of reputation and linked to network’s services to motivate vehicles to behave cooperatively during the first phase. …”
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Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study by Abduljaleel Abdullatif Zainel (18055382)

“…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …”

Social Network Analysis for Precise Friend Suggestion for Twitter by Associating Multiple Networks Using ML by Dharmendra Kumar Singh Singh (19517710)

“…This approach is by and large used to decrease the dimensionality of the information alongside its feature space. …”