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DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases
Published 2018“…Multivariate logistic regression analysis showed that DUSP1 and hsCRP are independently associated with CVD in the studied population, as reflected by 2-fold and 1.5-fold increased risks with increased levels of DUSP1 and hsCRP, respectively. …”
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162
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
Published 2020“…In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …”
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163
The effect of GLP-1R agonists on the medical triad of obesity, diabetes, and cancer
Published 2024“…While other GLP-1R agonists have shown promising outcomes in mitigating cancer progression, the association between some GLP-1R agonists and an increased risk of cancer remains a topic requiring more profound investigation. …”
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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …”
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Flexural strengthening of one-way reinforced concrete slabs using near surface-mounted BFRP bars
Published 2024“…<p>This study examines the flexural behavior of reinforced concrete (RC) one-way slabs strengthened with near-surface mounted (NSM) basalt fiber-reinforced polymer (BFRP) bars. …”
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168
Pregnant Women's experiences with intimate partner violence one year after the COVID‐19 pandemic in Jordan
Published 2023“…There were statistically significant (<i>p </i>≤ 0.05) higher mean DVQST scores for control IPV and psychological IPV during the pandemic (control IPV mean = 9.78, psychological mean = 7.03) versus before the pandemic (control IPV mean = 8.95, psychological mean = 6.62). …”
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Regulation of the aryl hydrocarbon receptor in cancer and cancer stem cells of gynecological malignancies: An update on signaling pathways
Published 2022“…One of the important pathways that mediates the metabolism and bioactivation of these environmental chemicals is the transcription factor, aryl hydrocarbon receptor (AhR). …”
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170
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
Published 2020“…Moreover, these extracts, mainly the hydroxytyrosol-rich extract, reduced the elevated liver enzymes, enhanced the antioxidant status, and attenuated the liver inflammation and apoptosis. …”
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Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study
Published 2024“…Hepatic glucose output increased from 0.6 (0.5–0.7) to 1.5 (1.3–1.7) mmol/min, while arterial lactate increased from 0.8 (0.7–0.9) to 9.0 (8.1–9.9) mmol/L (<i>P</i> < 0.05) despite a rise in hepatic lactate uptake. …”
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Evaluation of the mode I plastic zone size at the crack tip using RKPM and FEM
Published 2017“…In this study, it is proposed to obtain the mode I plastic zone size and shape at the crack-tip in a work-hardening material using RKPM. …”
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173
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
Published 2022“…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …”
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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (IEC), leading to increased ceramide levels. …”
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Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
Published 2011“…Purpose: The present study investigates the effect of a cell-free fraction of kefir on CEM and Jurkat cells, which are human T-lymphotropic virus type I (HTLV-1)-negative malignant T-lymphocytes. Methods: Cells were incubated with different kefir concentrations. …”
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176
Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
Published 2018“…PBA treatment, alone or with insulin induction, significantly increased glucose uptake in 3T3-L1 adipocytes. PBA significantly increased GLUT1 but not GLUT4 total protein expression. …”
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177
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…However, its role in hepatic steatosis and lipid accumulation is unknown. MALAT1 has recently attracted attention for its role in the evolution of diabetic complications, since it has been demonstrated that MALAT1 dysregulation contributes to the pathogenesis of diabetes and liver disease. …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”
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Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy
Published 2020“…<h3>Background</h3><p dir="ltr">Cardiac troponin I (<i>TNNI3</i>) gene mutations account for 3% of hypertrophic cardiomyopathy and carriers have a heterogeneous phenotype, with increased risk of sudden cardiac death (SCD). …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009)
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