Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S. El-Shoukrofy (19646815)

"…<p dir="ltr">A hybrid pharmacophore model, based on structural motifs previously identified by our team, was employed to generate ligands that simultaneously target COX-2, 15-LOX, and PPARγ in the context of metabolic dysfunction-associated fatty liver disease (MAFLD). Notable COX-2 inhibitory activities (IC₅₀ = 0.065–0.24 μM) were observed relative to celecoxib (IC₅₀ = 0.049 μM). …"

Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study حسب Abduljaleel Abdullatif Zainel (18055382)

"…Higher levels of anger, depression, and general anxiety were prevalent among 1.3% (n=84), 3.9% (n=260), and 1.6% (n=104) of participants, respectively. The mean score for the emotional constructs anger and depression decreased with increased compliance with regulations (<i>P</i>=.04 and <i>P</i>=.11, respectively). …"

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy حسب Olfa Khalifa (10914452)

"…<div><p>Non-alcoholic fatty liver disease (NAFLD) is a common liver lesion that is untreatable with medications. …"

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample حسب Menatalla Mekhaimar (14103708)

"…In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …"

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

"…<p dir="ltr">Age-related hearing loss (ARHL) is the most common sensory deficit in the elderly. …"

Reinforcement R-learning model for time scheduling of on-demand fog placement حسب Farhat, Peter

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Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment حسب Farhat, Peter

"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
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Evidence of a universal relation between electron-mode coupling and �� in Ba1−�⁢K�⁢Fe2⁢As2 superconductor from laser angle-resolved photoemission spectroscopy حسب Malaeb, W.

"…We attribute this kink to electron-mode coupling in good agreement with the inelastic neutron scattering (INS) and scanning tunneling microscopy (STM) results on the same compound where a similar bosonic mode associated with spin excitations was observed. The relation between the mode energy () and the SC transition temperature () deduced from our laser ARPES data follow the universal relation deduced from INS and STM. …"
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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... حسب Jaimie D Steinmetz (18015919)

"…We estimated the prevalence and relative contribution of avoidable causes of blindness and vision impairment globally from 1990 to 2020. …"

EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis حسب Yahya, Fares

"…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. The classification results show that the proposed methods outperform other related and competitive methods available in the literature and achieve 100% accuracy in subject-dependent and above 89% in subject-independent level in each of the four frequency bands. …"
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Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes حسب Ahmad Salman (3173418)

"…We, therefore, aimed to determine the sociodemographic, health-related behavior and clinical factors associated with meeting the recommended levels of physical activity in Scottish adults with diabetes. …"

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma حسب Peter Kubatka (11008854)

The Gulf Cooperation Council states: Crystallization of the regional cooperation and alliances amid dwindling resources حسب Evren Tok (14779270)

Influence of direct electric field on PMCG-alginate-based microcapsule حسب Peter Kasak (1360617)

Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial حسب Peter Oesch (3572426)

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage حسب Florence Hariton (18629764)

"…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …"

Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia حسب Sanaa Sharari (12561952)

"…<p dir="ltr">Accumulation of glycogen in the kidney and liver is the main feature of Fanconi–Bickel Syndrome (FBS), a rare disorder of carbohydrate metabolism inherited in an autosomal recessive manner due to SLC2A2 gene mutations. …"

State‐dependent control of breathing by the retrotrapezoid nucleus حسب Burke, Peter G. R.

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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... حسب Marissa B Reitsma (8674341)

"…We modelled multiple smoking-related indicators from 3625 nationally representative surveys. …"

Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors حسب Yu Wang (12152)

"…</p><p dir="ltr">Aerosol phase state is dependent on relative humidity (RH) and chemical composition (key factors determining aerosol water uptake). …"