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Over‐expression of the p110β but not p110α isoform of PI 3‐kinase inhibits motility in breast cancer cells
منشور في 2004"…Phosphoinositide 3-kinase (PI 3-kinase) activity is required for growth factor-induced cytoskeletal regulation and cell migration. …"
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202
How circular economy can reduce scope 3 carbon footprints: Lessons learned from FIFA world cup Qatar 2022
منشور في 2023"…However, such events also leave significant negative impacts on the environment such as an increase in greenhouse gas (GHG) emissions in the host and neighboring countries. …"
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203
Petrophilic, Fe(III) Reducing Exoelectrogen Citrobacter sp. KVM11, Isolated From Hydrocarbon Fed Microbial Electrochemical Remediation Systems
منشور في 2018"…The electrochemical activities of the strain KVM11 were characterized in a single chamber fuel cell and three electrode electrochemical cells. The inoculation of strain KVM11 amended with acetate and citrate as the sole carbon and energy sources has resulted in an increase in anodic currents (maximum current density) of 212 ± 3 and 359 ± mA/m<sup>2</sup> with respective coulombic efficiencies of 19.5 and 34.9% in a single chamber fuel cells. …"
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204
Subclavian pseudoaneurysm presenting as partially obstructed airway
منشور في 2023"…Managing the patient's airway posed significant challenges, including the risk of failed intubation, bleeding, and inability to oxygenate the patient.The case highlights the increasing importance of 3-Dimensional reconstruction computerized tomography in accurately diagnosing tracheal narrowing and compression. …"
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205
Additive Manufacturing of Polymer/Mg-Based Composites for Porous Tissue Scaffolds
منشور في 2022"…<div><p>Due to their commercial availability, superior processability, and biocompatibility, polymers are frequently used to build three-dimensional (3D) porous scaffolds. The main issues limiting the widespread clinical use of monophasic polymer scaffolds in the bone healing process are their inadequate mechanical strength and inappropriate biodegradation. …"
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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
منشور في 2022"…Although cardiac contractility was similar to the wild-type control, the ejection fraction was significantly increased in the mypbc3 mutants. At later stages of larval development, the mutants demonstrated an early cardiac phenotype of myocardium remodeling, concurrent cardiomyocyte hyperplasia, and increased ejection fraction as critical processes in HCM initiation to counteract the increased ventricular myocardial wall stress. …"
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207
MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles
منشور في 2020"…Exposure to hypoxia increased miR-24-3p in ECs but not in pericytes. Transfection with a miR-24-3p precursor (pre-miR-24-3p) increased miR-24-3p expression in ECs, reducing the cell survival, proliferation, and angiogenic capacity. …"
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208
Thermoelectric power of (Cu0.5Tl0.5)-1223 superconducting phase added with BaSnO3 nanoparticles
منشور في 2017"…In this study, we report the thermoelectric power (TEP) measurements of Cu0.5Tl0.5Ba2Ca2Cu3O10-δ added with BaSnO3 nanoparticles. BaSnO3 nanoparticles were prepared by chemical co-precipitation method, while (BaSnO3)x/(CuT1)-1223 superconducting samples with 0.00 ≤ x ≤ 1.50 wt% were prepared using the solid-state reaction method. …"
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209
Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
منشور في 2019"…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. Curcumin treatment increased the ratio of Bax/Bcl-2 and resulted in a leaky mitochondrial membrane that led to the discharge of cytochrome c from the mitochondria to the cytoplasm, the activation of caspase 3 and the cleavage of PARP. …"
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210
Thermal profiles of amorphous solid dispersions (ASD) in 3D printed tablets by fused deposition modelling (FDM): Production of tunable tablet doses
منشور في 2025"…Aptly, there was a 35% increase in solubility and a significant increase (<i>p</i> < 0.05) in dissolution rates of ibuprofen from 3D printed ASD tablets compared to printed tablets of pure ibuprofen. …"
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211
Modeling and Performance Analysis of mmWave and WiFi-Based Vehicle Communications
منشور في 2024"…<p dir="ltr">Vehicle -to-vehicle (V2V) communications are crucial for enhancing road network safety and efficiency. With the increasing demand for bandwidth in V2V services, exploring innovative solutions has become imperative. …"
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212
Microstructure and Compressive Behavior of Al–Y<sub>2</sub>O<sub>3</sub> Nanocomposites Prepared by Microwave-Assisted Mechanical Alloying
منشور في 2019"…The effect of different levels of yttrium oxide on the microstructural and mechanical properties of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites were investigated. The density of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites increased with increasing Y<sub>2</sub>O<sub>3</sub> volume fraction in the aluminum matrix, while the porosity decreased. …"
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213
Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy
منشور في 2023"…Early upregulation of Epac1 transcripts was noted in diabetic hearts at Week 4, followed by increases in Epac2 mRNA, but not protein levels, at Week 12. …"
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214
Enhanced nucleate boiling heat transfer on bubble-induced assembly of 3D porous interconnected graphene oxide/silver nanowire hybrid network
منشور في 2022"…<p>Due to an increasing trend of size diminution, integration, and multifunctionality, the heat load on electronic devices is constantly increasing. …"
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215
Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
منشور في 2017"…Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. …"
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216
The effect of graphene on the activation energy of grain growth for the nanocrystalline thermoelectric n-type Bi2Te2.7Se0.3
منشور في 2022"…The activation energy of the pristine Bi2Te2.7Se0.3 alloy is found to be 268 kJ/mol. For the composite samples, a lower graphene weight percentage (0.05 wt.%) increased the activation energy to 270 kJ/mol. …"
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217
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
منشور في 2025"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
منشور في 2008"…Results: WP1066 achieved an IC50 of 1.6, 2.3, and 1.5 μmol/L against melanoma cell line A375, B16, and B16EGFRvIII, respectively. …"
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220
Transport, magnetic and structural properties of(Tl0.5Pb0.5)Sr2-xCexCa2Cu3Oy compounds
منشور في 2000"…Resistivity, DC magnetization and X-ray diffraction measurements were performed on 6 sample with nominal composition (Tl0.5Pb 0.5)Sr2-xCexCa2Cu3 Oy, with x=0.0, 0.1, 0.2, 0.3, 0.4 and 0.5. As cerium content was increased, the transition temperature increased up to about 6 K when x=0.1. …"
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