Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…</p><p>ANGPTL3 is a protein secreted by the liver, belonging to the angiopoietin-like family of eight proteins. …"

Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice حسب Charlotte Rinne (18766966)

"…</p><h3>Methods</h3><p dir="ltr">Young and aged male C57Bl6J mice were subjected to CR for 8 weeks and were compared to age-matched littermates with free food access. …"

Dynamic stretching alone can impair slower velocity isokinetic performance of young male handball players for at least 24 hours حسب Monoem Haddad (5345357)

"…The objective of this study was to examine physiological responses of young trained athletes at 24-hours after experiencing SS or DS protocols. Eight young male, elite handball players (age: 16.1±5.1 years) were tested prior to-, 3-minutes and 24-hours following the three conditions (DS, SS, Control) in a randomized and counterbalanced order. …"

Pathology of the liver in obese and diabetic ob/ob and db/db mice fed a standard or high-calorie diet حسب Nasser, Selim

"…Non-alcoholic fatty liver disease (NAFLD) is one of the commonest liver diseases in Western countries. …"
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Risk factors for early death due to recurrence after liver resection for hepatocellular carcinoma: Results of a multicenter study حسب Abdalla, Eddie

"…Of these, 53 (43%) died of recurrence, 30 (24%) of post-operative complications, and 40 (33%) of liver failure/hemorrhage. On multivariateanalysis, tumor size greater than 5 cm (P < 0.02; odds ratio, 3.0), multiple tumors(P < 0.01; odds ratio, 3.3), and greater than 5 mitoses per 10 high-power fields(P < 0.03; odds ratio, 3) were associated with increased risk of early death due torecurrence.Conclusions: These findings enable identification of patients with HCC who are athigh risk for early death due to recurrence following potentially curative resection whomight be candidates for adjuvant therapy trials.…"
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Bevacizumab Improves Pathologic Response and Protects Against Hepatic Injury in Patients Treated With Oxaliplatin-Based Chemotherapy for Colorectal Liver Metastases حسب Ribero, David

"…The current study evaluated the effect of bevacizumab added to fluoropyrimidine-plus-oxaliplatin (5FU/OX) chemotherapy for colorectal liver metastases (CLM) on the pathologic response and nontumorous liver histology. …"
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... حسب Masri, Oussama Samer

"…Purpose Establishing the reliability of a new method to check the mean retinal and choroidal reflectivity and using it to find retinal and choroid changes in amblyopia. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case حسب Okan Sirin (14603304)

"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"

Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepat... حسب Rubbia-Brandt, Laura

"…Rubbia-Brandt L, Lauwers G Y, Wang H, Majno P E, Tanabe K, Zhu A X, Brezault C, Soubrane O, Abdalla E K, Vauthey J-N, Mentha G & Terris B (2010) Histopathology56, 430–439 Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis Aims:  Because of its efficacy, oxaliplatin (OX) is increasingly used as a chemotherapeutic agent in the treatment of colorectal liver metastases (CRLM). …"
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Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study حسب Abeer A Omar (21623774)

"…</p><h3>Results</h3><p dir="ltr">A total of 825 participants with mean age 29.2 years (5.9) of which 365 (44.2%) were males. …"

Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats حسب Ines Fki (14571855)

"…The current research showed that the treatment with the HFD increased the body weight and adipose tissue mass in male rats. …"

Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study حسب Stefanos Volianitis (22155835)

"…Hepatic glucose output increased from 0.6 (0.5–0.7) to 1.5 (1.3–1.7) mmol/min, while arterial lactate increased from 0.8 (0.7–0.9) to 9.0 (8.1–9.9) mmol/L (<i>P</i> < 0.05) despite a rise in hepatic lactate uptake. …"

The Superiority of T2*MRI Over Serum Ferritin in the Evaluation of Secondary Iron Overload in a Chronic Kidney Disease Patient: A Case Report حسب Abdulrahman Al-Mashdali (16388474)

"…Currently, T2*MRI of the heart and liver is the preferred investigation for evaluating liver iron concentration (LIC) and cardiac iron concentration, which reflect the state of iron overload. …"

The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study حسب Richard Charles Franklin (9154052)

"…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …"

Downregulation of <i>CYP17A1</i> by 20-hydroxyecdysone: plasma progesterone and its vasodilatory properties حسب Maneera Y Aljaber (18278971)

"…Methods: Chimeric mice with humanized liver were treated with 20-hydroxyecdysone for 3 days, and hepatic steroidogenic pathway genes and plasma progesterone were measured by transcriptomics and GC–MS/MS, respectively. …"

Efficient Detection of Hepatic Steatosis in Ultrasound Images Using Convolutional Neural Networks: A Comparative Study حسب Fahad M. Alshagathrh (19365478)

"…<h3>Introduction</h3><p dir="ltr">Artificial Intelligence (AI) is widely used in medical studies to interpret imaging data and improve the efficiency of healthcare professionals. Nonalcoholic fatty liver disease (NAFLD) is a common liver abnormality associated with an increased risk of hepatic cirrhosis, hepatocellular carcinoma, and cardiovascular morbidity and mortality. …"

Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar حسب Dalal Al‐Sharshani (19479814)

"…<h3>Background</h3><p dir="ltr">Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD).</p><h3>Objective</h3><p dir="ltr">The study aimed to investigate the association between selected single nucleotide polymorphisms (SNPs) with dyslipidemia and increased susceptibility risks of CVD, NAFLD, and/or T2DM in dyslipidemia patients in comparison with healthy control individuals from the Qatar genome project.…"

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... حسب Haidong Wang (47381)

The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global... حسب Farin Kamangar (63964)

"…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …"

Exercise-induced Citrate Enhances Associative Memory Formation by Modulating Histone Acetylation in a Sex-dependent manner حسب El Masri, Diala

"…This increase is accompanied with a decrease in hippocampal HDAC2, leading to the expression of immediate early genes involved in synaptic plasticity. …"
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