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Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
منشور في 2018"…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …"
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42
A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor
منشور في 2022"…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M<sup>pro</sup> activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M<sup>pro</sup> and functional genomics application to determine the effect of sequence variation in M<sup>pro</sup>.…"
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43
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
منشور في 2021"…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …"
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44
The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20...
منشور في 2020"…The age-standardised death rate decreased from 0·61 (0·55–0·69) per 100 000 population in 1990 to 0·51 (0·42–0·54) per 100 000 population in 2017. …"
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45
Impact of Work-Life Balance on Female Employee Motivation
منشور في 2023"…The results of the study demonstrated the importance of work-life balance to women's personal lives. Many working women are able to balance their careers and personal lives successfully because they have flexible schedules, are married, or earn a generous salary. …"
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46
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
منشور في 2021"…</p><p dir="ltr">Aerosol phase state is dependent on relative humidity (RH) and chemical composition (key factors determining aerosol water uptake). …"
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47
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
منشور في 2020"…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …"
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48
Central and peripheral muscle fatigue following repeated‐sprint running in moderate and severe hypoxia
منشور في 2020"…No significant differences between conditions for mean distance occurred in set 2. There was a decrease in maximal voluntary contraction torque (Δ = −31.4 ± 18.0 N m, <i>P</i> < 0.001) and voluntary activation (%VA; Δ = −7.1 ± 5.1%, <i>P</i> = 0.001) from Pre- to Post-set 1, but there was no effect of hypoxia. …"
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49
Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study
منشور في 2025"…The female/male ratio was 17.5%/82.5%, and the mean injury severity score was 13 ± 9. …"
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50
The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
منشور في 2023"…Females who started smoking last year were 2.6‐fold more than males (<i>p</i>< 0.0001). We also noticed that there is a significant relationship between those who started smoking and are <18 years, living in a family consisting of seven members or more, being unemployed, having a diploma or bachelor's degree in a health‐related major, having no chronic illnesses, increasing of daily meals or night meals, almost daily sugar intake, starting to follow social media account concerning physical activity, exercising once or twice a week, and sleeping more hours per day since the beginning of the pandemic (<i>p</i> < 0.01).…"
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51
Impact of Life-coaching on Students' Wellbeing and Engagement Levels in a Preparatory School in Qatar
منشور في 2019"…The sample consisted of 40 male students aged between 13 and 16 years old (mean age 14.2). …"
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52
Short-term outcomes of anterior cruciate ligament reconstruction with or without lateral tenodesis or anterolateral ligament reconstruction: a retrospective cohort
منشور في 2023"…However, there was a significant decrease in postoperative flexion in the ACL and ALL reconstruction group by a mean of 22° (95% CI − 40.7 − 3.4; P = 0.02) at 6 weeks compared to ACLR alone, which was not evident on later follow-ups.…"
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53
Effect of Hypoxia on Maximal Fat Oxidation Rate During Incremental Cycling : Relationship to the Gas Exchange Threshold
منشور في 2024"…This suggests the reduced fat oxidation was not fully accounted for by a decrease in absolute work rate alone which occurred due to normalization of relative intensity in HYPO, but an independent effect of reduced oxygen availability may affect regulation of substrate utilization. …"
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54
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…Findings: The global number of new episodes of URIs was 12·8 billion (95% uncertainty interval 11·4 to 14·5) for all ages across males and females in 2021. The global all-age incidence rate of URIs decreased by 10·1% (–12·0 to –8·1) from 1990 to 2019. …"
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55
Driving simulation sickness and the sense of presence: Correlation and contributing factors
منشور في 2021"…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …"
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56
Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
منشور في 2023"…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …"
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57
Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
منشور في 2023"…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …"
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58
Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy
منشور في 2021"…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …"
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59
Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of...
منشور في 2021"…Age-standardised death rate decreased by 15.7% (8.6 to 21.0), during the period 1990–2019. …"
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60
The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention
منشور في 2025"…Additionally, the lidocaine group had a relatively small change in HR, with a mean difference of -10.56 (95% CI -13.30 to -7.83 beat per minute, <i>P</i> = 0.00001). …"