SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs حسب Raed Shalaby (3756112)

"…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…"

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes حسب Muhammad Danyal Ahsan (14488278)

"…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …"

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity حسب Qinji Zhou (18513741)

"…Mice with conditional knockout (cKO) of Celsr3 in postnatal PCs exhibit deficit in motor coordination and learning, atrophic PC dendrites, and decreased synapses. Whole-PC recording in cerebellar slices discloses a reduction frequency of mEPSC and defective postsynaptic plasticity (LTP and LTD) in Celsr3 cKO mutants. …"

Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates حسب Fariha Niaz (14778319)

"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"

Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete حسب Alaa Taha (17302783)

"…Results showed a slight reduction in bond strength, minor improvement in normalized bond strength, increased development length of FRP bars, and decreased reinforcement slippage associated with the ultimate bond stress when MWCNTs were incorporated into the concrete mixture. …"

Thermodynamic analysis of solar-driven integrated system for efficient brine management and hydrogen production حسب Nadira Salsabila (16855101)

"…The PEM fuel cell generates 4.9 kW of electricity, though its efficiency decreases with higher current density.</p><h2>Other Information</h2> <p> Published in: International Journal of Hydrogen Energy<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.ijhydene.2024.12.428" target="_blank">https://dx.doi.org/10.1016/j.ijhydene.2024.12.428</a></p>…"

Application of Low-Fermenting Yeast Lachancea thermotolerans for the Control of Toxigenic Fungi Aspergillus parasiticus, Penicillium verrucosum and Fusarium graminearum and Their M... حسب Randa Zeidan (14778388)

"…Very interestingly, it was shown that even 7 yeast colonies reduced <i>Fusarium’s</i> growth and the synthesis of its mycotoxin, deoxynivalenol (DON). Moreover, decreasing yeast nutrient concentrations did not affect the inhibition of fungal growth, but reduced DON synthesis. …"

Morphology Control of TiO₂ Nanorods Using KBr Salt for Enhancing the Photocatalytic Activity of TiO₂ and MoS₂/TiO₂ Heterostructures حسب Zeineb A. Thiehmed (15945042)

"…This results in affecting the morphology by decreasing the diameter of the nanorods, and increasing the free space between them. …"

Aorta deformation linked to heart disease حسب Nature Research (16552612)

"…</p><p></p><h2>Other Information</h2><p>Published in: QScience.com Highlights, Published by Nature Research for Hamad bin Khalifa University Press (HBKU Press)<br>License: <a>http://creativecommons.org/licenses/by/4.0></a></p>…"

Pilot testing of a novel Multi Effect Distillation (MED) technology for seawater desalination حسب Shahzada Aly (17191465)

"…By implementing this invention's design, the heat transfer area has been decreased and accordingly, the capital cost of the evaporator is reduced by 20%. …"

Trace Element Composition of Plankton from the Qatari Exclusive Economic Zone (EEZ) of the Arabian Gulf حسب Oguz Yigiterhan (14151006)

"…Dust in Qatar is depleted in aluminum and enriched in calcium relative to global average Upper Continental Crust due to the geology of the outcropping sedimentary rocks and topsoil in the source areas of the dust.The excess concentrations relative to average dust from Qatar for most trace elements decreased with distance from shore. This may be due to large scale of dust input to the nearshore surface waters in the Gulf. …"

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model حسب Haissam Abou-Saleh (497840)

"…By reporting new insights on their organ-specific toxicity, our results add novel and useful information into the available data concerning the in vivo effect of ChNPs.…"

Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system حسب Mohammadreza Gholami (17032317)

"…The MREAI and MREEI offer additional information beyond LOLE and EENS, specifically highlighting the contribution of RESs to the availability and energy losses in the MG. …"

The Economic Impact of Optimizing a COVID-19 Management Protocol in Pre-Existing Cardiovascular Disease Patients حسب Dina Abushanab (10696501)

"…<p>This study answers the question of whether the health care costs of managing COVID-19 in preexisting cardiovascular diseases (CVD) patients increased or decreased as a consequence of evidence-based efforts to optimize the initial COVID-19 management protocol in a CVD group of patients. …"

Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection حسب Rabah Ismaen (18387189)

"…The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. The T-DCS configuration becomes economically competitive only at high electricity tariffs.…"

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice حسب Ayman Alzu'bi (18192898)

"…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …"

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders حسب Jaunetta Hill (18255631)

"…Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …"

Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice حسب Tomas Venit (17248420)

"…These changes are associated with reduced OXPHOS gene expression, decreased mitochondrial DNA copy number, and deregulated mitochondrial dynamics, which lead to metabolic reprogramming of NM1 KO cells from OXPHOS to aerobic glycolysis.This, in turn, is associated with a metabolomic profile typical for cancer cells, namely increased amino acid-, fatty acid-, and sugar metabolism, and increased glucose uptake, lactate production, and intracellular acidity. …"

Sulfobetaine-based polydisulfides with tunable upper critical solution temperature (UCST) in water alcohols mixture, depolymerization kinetics and surface wettability حسب Jozef Kollár (8121347)

"…Tunable surface wettability were shown on the grafted polymers. Findings: Decreasing polarity and/or increasing alcohol percentage in the water mixtures induced an increase in the cloud points of the polymers in the solutions. …"

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

"…Thus, a screening of a cohort of ARHL patients and controls was carried out revealing several variants inSLC7A8, whose role was further investigated by in vitro functional studies. Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …"