Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …”

Essays on Renewable Energy Dynamics & Co₂ Emissions: Insights From Selected OIC Countries and World Nations by Javid Aliyev (19325665)

“…The results reveal that renewable energy consumption has a negative impact on CO₂ emissions, while real GDP per capita has a positive effect. …”

Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H₂S: DFT study by Ehab Salih (17075206)

“…Moreover, the adsorption distance (D) between H₂S and Cu/Zn-ZGNR decreased remarkably to 2.23 Å and an S–Cu bond was generated. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…MALAT1 (metastasis associated with lung adenocarcinoma transcript 1) is a well-conserved lncRNA that has been linked to a variety of illnesses, including cancer. …”

Crunching the numbers of food poisoning in Qatar by Nature Research (16552612)

“…<p>Salmonellosis is a common type of food poisoning caused by <i>Salmonella</i> bacteria. …”

Use of Carbide Derived Carbon in Water Treatment and Thermal Fluids Applications by Ismail W. Almanassra (14151321)

“…Water scarcity is a global issue due to the increasing demand and consumption of natural water resources, which are under stress from; a growing human population, decreasing ground water tables and precipitation, and increasing agriculture, industrialization and urbanization. …”

Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient by Iman Hawari (12561958)

“…However, aggregates related to CD71+ erythroid cells, which have immunosuppressive characteristic, were highly upregulated in the LRBA-deficient patients.Experimental analysis of MIN6 cell in culture revealed that in siRNA-mediated-knockdown of LRBA revealed a significant decreased intracellular proinsulin and mature insulin inside β-cells in comparison so the wild type cells. …”

The immune landscape of solid pediatric tumors by Shimaa Sherif (12862990)

“…</p><h3>Methods</h3><p dir="ltr">We performed a systematic analysis of public RNAseq data (TARGET) for five pediatric tumor types (408 patients): Wilms tumor (WLM), neuroblastoma (NBL), osteosarcoma (OS), clear cell sarcoma of the kidney (CCSK) and rhabdoid tumor of the kidney (RT). …”

Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome by Sanaa Ali Sharari (19953093)

“…It is inherited in an autosomal recessive manner due to<i> SLC2A2 </i>gene mutations. <i>SLC2A2</i> encodes for glucose transporter 2 (GLUT2) which is a low-affinity facilitative transporter of glucose; it is mainly expressed in tissues that are significantly involved in glucose homeostasis. …”

Impact of Work-Life Balance on Female Employee Motivation by Haleema Raja (22196926)

“…The study has revealed a link between work-life balance and employee motivation, suggesting that businesses that prioritize work-life balance policies will likely experience better levels of employee engagement, Productivity, well-being, retention, and decreased levels of stress. …”

Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer by Ahmed Mahmoud Mahmoud Mohamed Kardousha (19926096)

“…Although, death rates due to BC have consistently decreased over time, TNBC still poses a challenge due to its poor prognosis, high rates of relapse and resistance to chemotherapy. …”

Visible Light Photocatalytic Activity of Ag/WO₃ Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark by Maha Matalkeh (17148358)

“…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. …”

Providing Health Care in Armed Conflict Countries: The Case of Yemen by Esraa Ali Sayed Ali (20741327)

“…These challenges can be classified into two categories, first, administrative challenges related to difficulties faced by humanitarian organizations in introducing and delivering health services to the Yemeni Population Second, technical challenges related to health system constrains, this is due to the impact of the conflict on health</p><h3>Conclusion</h3><p dir="ltr">Since the complex, interlocking layer of conflict is not the only way to address the humanitarian crisis in Yemen, there are certain opportunities that focus on decreasing the effect of the war on the people of Yemen whilst still waiting for a political solution. …”

Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure by Mineko Baba (19774386)

“…<p dir="ltr">For the last fourteen years in Japan, casualties due to traffic collisions have decreased. There were 9,073 traffic fatalities in 2000 and 4,113 in 2014. …”

Biomarkers show promise for treatment of heart valve disease by Nature Research (16552612)

“…For example, previous studies have shown that replacement valves originating from animal tissue (bioprostheses) become calcified in patients with increased 1 levels of a type of low-density lipoprotein particles. The researchers suggest that patients with increased pro- or decreased anti-calcific factors in their serum should avoid replacement with a bioprosthesis. …”

Examining time-to-transport decisions in Emergency Medical Services by Hassan Farhat (9000509)

“…As the time spent on scene increases (due to various reasons, among them: spending more time providing clinical treatment and health education because the patient decided not to go to the hospital, or the crew spending more time convincing the patient to go to the hospital by explaining the potential complications of their condition and the potential outcomes of a refusal to go to hospital), the probability of transporting the patient decreases. …”

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project by Mariam Al-Mutawa (18505317)

“…Medical devices contribute to approximately 50% of these total HAPI. HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …”

Essays on Digital Financial Inclusion and Financial Resilience for Sustainable Development in Sub-Saharan Africa by Jamila Abubakar (22653059)

“…A significant body of literature suggests the SSA’s middle class’s vulnerability to financial shocks, and our findings, indicating savings volatility and decreased savings accumulation due to financial shocks for the middle-income class groups, support these claims. …”

Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans by Kevin S. Chen (9201767)

“…<h3>Background</h3><p dir="ltr">Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. …”