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221
mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation
منشور في 2017"…In mice with conditional epidermal loss of the mTORC1 components Rheb or Rptor, mTORC1 loss of function unexpectedly resulted in a profound skin barrier defect with epidermal abrasions, blistering, and early postnatal lethality, due to a thinned epidermis with decreased desmosomal protein expression and incomplete biochemical differentiation. …"
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222
Modeling circadian clock–cell cycle interaction effects on cell population growth rates
منشور في 2014"…Particularly, we show that Cry 1, Cry 2 mutations decrease the growth rate of cells, Per 2 mutation enhances it and Bmal 1 knockout increases it for autonomous periods of the cell cycle less than 21 h and decreases it elsewhere. …"
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223
Project Portfolio Management for Successful Major IT Projects in Global Telecommunication Organization
منشور في 2011"…Human resource function is vital to develop the required skills according to the new requirements of the organization projects.Mainly, it is suggested by this paper that the association of these factors should be investigated in future studies using a larger sample of questionnaire respondents and to different telecommunication organizations.…"
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224
Differential water quality in confined and free-flowing water bodies, Lebanon
منشور في 2003"…This emphasises the importance of assessing surface water quality as a projected means to increase water availability. This study involves two different water bodies, the freely flowing Nahr-Ibrahin River and the Qaraaoun Reservoir, an impoundment of the Litani River. …"
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225
Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
منشور في 2019"…The quantification of mental states was performed by means of statistical analysis of indexes based on GTA, behavioral responses of time-on-task (TOT), and Brunel Mood Scale (BRMUS). …"
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226
Cycling and regeneration of adsorbed natural gas in microporous materials
منشور في 2017"…While research in this field is mainly devoted to optimizing the gravimetric and volumetric storage capacity of methane, this work investigates the long-term effect of large alkanes on natural gas storage. …"
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227
Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
منشور في 2023"…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …"
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228
The Impact of Different Urban Configurations on Outdoor Thermal Comfort: A Case Study of the Military Camps in Abu Dhabi, UAE
منشور في 2016"…Computer simulation was preferred as the main methodology in this research and ENVI-met 4.0 software was used as the main simulation tool. …"
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229
Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat
منشور في 2006"…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …"
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230
A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV
منشور في 2010"…Possible consequences could be altered signalling at the cell surface triggered by DRM-associated proteins, with implications on gene regulation and subsequent protein expression.…"
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231
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
منشور في 2019"…The accumulation of aberrant DNA methylation and histone acetylation plays a major role in altering gene activity and driving tumor onset, progression and metastasis. …"
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232
A simple quality-of-service-based connection setup management approach for optical networks
منشور في 2017"…The previous claim is asserted through our simulation results that gauge the main benefits behind our proposed connection setup strategy. …"
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233
Driving simulation sickness and the sense of presence: Correlation and contributing factors
منشور في 2021"…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …"
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234
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
منشور في 2020"…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …"
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235
Developing a Stochastic Model to Predict Cost Overrun due to the Causes of Projects Delay in Oil Fields Construction Industry
منشور في 2020"…The main contribution of this work, is the research framework which can be used by businesses in oil fields construction industry to model their own factors and help in their decision-making, as opposed to using anecdotal evidence. …"
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236
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
منشور في 2014"…Conclusions These results suggest that the pentane-based fractions of DCOE possess potential anti-cancer activity that is mainly mediated through the Erk pathway.…"
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237
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
منشور في 2021"…The performance of the FDD method depends mainly on the quality of the extracted features including real-time changes, phase changes, trend changes, and faulty modes. …"
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238
Investigating the Properties of Electrodeposited of Ni-P-ZrC Nanocomposite Coatings
منشور في 2021"…<p dir="ltr">Superior corrosion resistance along with higher mechanical performance is becoming a primary requirement to decrease operational costs in the industries. Nickel-based phosphorus coatings have been reported to show better corrosion resistance properties but suffer from a lack of mechanical strength. …"
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239
Privacy-Preserving Fog Aggregation of Smart Grid Data Using Dynamic Differentially-Private Data Perturbation
منشور في 2022"…<p>The edge of the smart grid has a massive number of power and resource-constrained interconnected devices. Mainly, smart meters report power consumption data from consumer homes, industrial buildings, and other connected infrastructures. …"
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240
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…Compound 2a activated PPARγ with an EC50 value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …"
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