The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…We also observed the differential expression of protein Complement C3 (3.3-fold), Destrin (−5.1-fold), Vimentin (−1.7-fold), Peroxiredoxin 4 (−1.6-fold), Fascin (−1.8-fold), Heme oxygenase-2 (−0.67-fold**p < 0.0055), Hsp27 (−0.57-fold**p < 0.004), and Hsp70 (−0.39-fold **p < 0.001), indicating reduced cell growth, cell migration, and metastasis. …”

Acute pain management and assessment by Zeitoun, Abeer A.

“…Methods  A Lebanese multi-centre, prospective, chart review study was conducted over a period of 3 months. Data on demographics, pain medication, dose, route, duration and adjunct pain management were collected. …”
Get full text
Get full text
Get full text

P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis by Milane, Aline

Get full text
Get full text
Get full text
Get full text

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 by LBD Double Burden of Malnutrition Collaborators (18567880)

“…Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. …”

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S., El-Shoukrofy

“…Compound 2a activated PPARγ with an EC50 value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …”
Get full text
Get full text
Get full text

PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
Get full text
Get full text
Get full text

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
Get full text
Get full text
Get full text
Get full text

Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection by Rabah Ismaen (18387189)

“…The PV-DCS configuration is economically competitive among the solar assisted cooling systems, and it can contribute to reducing the environmental impact by 58.3%. The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. …”

The English Language Centre Community College Qatar: A Position Report by Irum Naz (17948078)

“…The idea of integrating skills was also put forth as a means of increasing the efficiency of the program and rendering it more cost effective. …”

The power of local media as an actor in the international system. (2013) by Abed, Claudette

Get full text
Get full text

Driving toward hydrogen mobility: A life cycle cost analysis of conventional, electric, and hydrogen fuel cell vehicles in Qatar by Carlos Méndez (88102)

“…To mitigate this, the nation has introduced electrified means of transport such as <u>metro</u>, tram, and buses. …”

Designing for Digital Wellbeing: From Theory to Practice a Scoping Review by Reem S. Al-Mansoori (18103045)

“…Our analysis identified different meanings and constructs of the Digital Wellbeing concept, research trends, and a gap related to incorporating it in the design process. …”

Ajaaj and National Identity: A Comic Book with a Serious Mission by Al Owais, Fatima Sultan

Get full text

HOW TO PROMOTE MEDIATION OF CONSTRUCTION DISPUTES IN THE UAE by Yumna, Saem Aldaher

“…Furthermore, the fact that the parties involved in the execution of construction contracts who are coming from different cultural background, personalities and a set of expectations also contribute to increasing the possibility of disputes and conflict in the construction industry. …”
Get full text

A Critical Assessment of the Readiness of the Project Management Profession to Industrial Revolution 4.0 in the UAE by Abdalla, Hiba

“…However, the research has found that most project managers in the United Arab Emirates are barely ready for industry 4.0; most of them are not aware of what the term “industry 4.0” means. Additionally, they lack the skills needed to become successful project managers in the new revolution. …”
Get full text

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity by Mohammed R. Shaker (10316180)

“…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

“…The graphical simulations are performed for flow parameters with specific range like 1≤Re≤5, 1≤Ha≤5, 0.5≤Nt≤2.5, 1≤Nb≤3, 0.2≤Sc≤1.8, 0.2≤Pe≤1.0 and 0.2≤Ω≤1.0. It is observed that the flow velocity decreases with the increase in the Hartmann number that signifies the magnetic field. …”

Performance of Membrane Biological Reactor for Tobacco Wastewater Treatment by Alhajar, Abdallah Hazim Abdallah

Get full text

In-Vehicle Performance Validation of the Semi-Active Hybrid Energy Storage System by Rehman, Habib-ur

“…The UCs supply the dynamic component of the load current which decreases the battery size, limits the battery peak current, and extends its life. …”
Get full text

Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications by Tooba Yasin (19131382)

“…It was found that increasing ZiF-8 decreases the swelling in different media and increases degradation in PBS media. …”