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IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…Background: In inflammatory bowel disease (IBD), cytokine levels (such as interleukin-1 (IL-1)) are elevated. We have shown previously that IL-1 activates phospholipid signaling pathways in intestinal epithelial cells (IEC), leading to increased ceramide levels. …”
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182
Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
Published 2011“…Purpose: The present study investigates the effect of a cell-free fraction of kefir on CEM and Jurkat cells, which are human T-lymphotropic virus type I (HTLV-1)-negative malignant T-lymphocytes. Methods: Cells were incubated with different kefir concentrations. …”
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183
Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes
Published 2018“…PBA treatment, alone or with insulin induction, significantly increased glucose uptake in 3T3-L1 adipocytes. PBA significantly increased GLUT1 but not GLUT4 total protein expression. …”
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184
Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…<h3>Introduction</h3><p dir="ltr">Left ventricular thrombus (LVT) increases the risk of ischemic stroke. However, it remains uncertain if the percutaneous coronary intervention (PCI) in the confirmed LVT setting further augments the stroke risk. …”
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185
MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the...
Published 2020“…SMAD2 was identified as bone fide gene target for miR-3148 using qRT-PCR, Western blotting, and UTR-based reporter assay. …”
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186
Founder Mutation in N Terminus of Cardiac Troponin I Causes Malignant Hypertrophic Cardiomyopathy
Published 2020“…<h3>Background</h3><p dir="ltr">Cardiac troponin I (<i>TNNI3</i>) gene mutations account for 3% of hypertrophic cardiomyopathy and carriers have a heterogeneous phenotype, with increased risk of sudden cardiac death (SCD). …”
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187
Characterization of Dse1 a candida albicans cells wall protein. (c2009)
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188
Decoding the Therapeutic Potential of [HuArgI (Co)-PEG5000] Arginase Treatment
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189
The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
Published 2022“…We have previously demonstrated that one of these transcription factors, SREBP1, is stabilized and remains associated with target promoters during mitosis, suggesting that the expression of these target genes could be important as cells enter G1 and transcription is restored. …”
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190
Deficiency in the endocytic adaptor proteins PHETA1/2 impair renal and craniofacial development
Published 2020“…Deficiency of pheta1/2 resulted in dysregulation of cathepsin K, which led to an increased abundance of type II collagen in craniofacial cartilages, a marker of immature cartilage extracellular matrix. …”
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191
Designing Low Frequency I.C Filter Using Pseudo Resistor for Biopotential Measurements
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192
The effects of Social Determinants of Health on Type 2 Diabetes Outcomes (A1C)
Published 2020“…Diabetes duration of 5-10 years increased the odds of having uncontrolled A1C by more than 3 folds. …”
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193
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…Furthermore, confocal microscopy analysis of BODIPY-stained untreated, steatotic, and Ex-4-treated steatotic cells showed that Ex-4 significantly decreases the number of lipid droplets. Fatty acid uptake and transport genes were also affected by MALAT1 knockdown. …”
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194
I’m no casual: exploring the consumer behaviour of Fantasy Premier League hardcore international managers
Published 2023“…Using interviews and applying Grounded Theory, this study offers a description regarding managers’ 1) perceptions of what makes a hardcore manager as against a casual one; 2) motivations to participate in FPL at hardcore levels; 3) media usage; 4) the impact FPL has on their consumption of the sport and its products; and 5) the marketability of specific players. …”
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196
Reliability and fault tolerance based topological optimization of computer networks - part I: enumerative techniques
Published 2003“…We consider fault tolerance to be an important network design aspect In this paper, we propose one algorithm for optimizing the terminal reliability and another for optimizing the network reliability while improving the fault tolerance aspects of the designed networks. …”
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197
A photoactivatable Ru (II) complex bearing 2,9-diphenyl-1,10-phenanthroline
Published 2021“…The photoactivatable Ru (II) complex 1 [Ru(bipy)2(dpphen)]Cl2 (where bipy = 2,2′-bipyridine and dpphen = 2,9-diphenyl-1,10-phenanthroline) has been shown to possess promising anticancer activity against triple negative adenocarcinoma MDA-MB-231 cells. …”
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198
Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis
Published 2021“…Septic stimulation induced a significant increase in ERLIN1 expression; however, ERLIN1 was differentially expressed among the immune blood cell subsets. …”
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Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report
Published 2018“…The NY-ESO-1-specific T cells response of the patient was found to be increased after the third and the fifth (**p = 0.002) cycles of treatment but had a significant decline after progression (**p = 0.0028). …”
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Enhanced optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>-<sub><em>x</em></sub>S<sub><em>x</em></sub>S: A DFT study
Published 2025“…Here, we conduct systematic density functional theory calculations to study the effect of sulfur doping on the electronic and optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>. We find that the band gap of the material decreases with increasing sulfur content (from 4.81 eV to 1.59 eV), accompanied by symmetric shifts in both the valence-band offset and the conduction-band edge. …”