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481
Heat Transfer Coefficient Estimation of Falling Film for Horizontal Tube Multi-Effect Desalination Evaporator Using CFD
منشور في 2021"…Furthermore, the higher operating temperature limit should be increased instead of decreasing operating temperature for improved heat transfer performance.…"
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482
Techno-economic and environmental analyses of the pyrolysis of food waste to produce bio-products
منشور في 2024"…The water footprint increased with increasing pyrolysis temperature but decreased with increasing moisture content in all scenarios. …"
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483
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"
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484
Exploring Unique Physiological and Genetic Features of Desert-dwelling Legumes
منشور في 2025"…<p dir="ltr">The widespread Fabaceae family is the third largest group of flowering plants, thriving across diverse seasonal and climatic conditions, including arid, harsh desert regions. Legumes are always meeting consumers’ preferences because of their high protein content, oil-producing grains (soybeans, peanuts), and incredible therapeutic properties. …"
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485
Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
منشور في 2020"…Interestingly, we also found that inhibition of autophagy in exercising 10-week-old mice decreases BDNF protein levels in the hippocampus as compared to the control exercising group. …"
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masterThesis -
486
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). …"
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article -
487
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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masterThesis -
488
Sulfobetaine-based polydisulfides with tunable upper critical solution temperature (UCST) in water alcohols mixture, depolymerization kinetics and surface wettability
منشور في 2021"…The regeneration of monomers by depolymerization was tunable by temperature and sunlight. A thickness dependence on surface wettability was observed on wafers covalently modified with polydisulfides. …"
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489
Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation
منشور في 2024"…Qualitative description of the experimental results is given through bond distance-dependent total energy calculations and structural and electronic structure analysis within density functional theory. …"
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490
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery – A Follow-Up Study...
منشور في 2021"…</p><h3>Results </h3><p dir="ltr">The means (SD) of age and BMI of class III obesity subjects was 32.32 (8.36) years and 49.02 (6.28) kg/m<sup>2</sup>, respectively. …"
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491
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
منشور في 2024"…FindingsFrom 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. …"
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article -
492
Breathing regulation and blood gas homeostasis after near complete lesions of the retrotrapezoid nucleus in adult rats
منشور في 2018"…In conclusion, near complete RTN destruction in rats virtually eliminates the CRC but the HVR persists and sighing and the state dependence of breathing are unchanged. Under normoxia, RTN lesions cause no change in VE but alveolar ventilation is reduced by at least 21%, probably because of increased physiological dead volume. …"
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article -
493
Hippocampal Programmed Cell Death after Status Epilepticus
منشور في 2003"…Summary: Purpose: Status epilepticus (SE) can result in acute neuronal injury with subsequent long-term age-dependent behavioral and histologic sequelae. To investigate potential mechanisms that may underlie SE-related neuronal injury, we studied the occurrence of programmed cell death (PCD) in the hippocampus in the kainic acid (KA) model. …"
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article -
494
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495
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496
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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article -
497
Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
منشور في 2009"…Pretreatment with the extract (50, 100 and 200mg/kg BW by gastric gavage) produced a dose dependent protection against gastric ulcer induced by 60% ethanol. …"
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article -
498
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499
Enhanced optical properties of <i>β</i>-Ga<sub>2</sub>O<sub>3</sub>-<sub><em>x</em></sub>S<sub><em>x</em></sub>S: A DFT study
منشور في 2025"…Consequently, the absorption intensity in the visible and UV ranges of the spectrum increases by more than an order of magnitude, depending on the level of doping, with a clear red shift. …"
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500
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Interestingly, the silencing of β-catenin with siRNA abolished the effect of Ex-4 on these genes, suggesting dependency on the Wnt/β-catenin pathway. Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"