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521
Oxandrolone Treatment in Adults with Severe Thermal Injury
منشور في 2009"…Multicenter, prospective, randomized studies are needed to better define the optimal oxandrolone dosage and to confirm the efficacy and safety of this drug in adult patients with severe thermal injury.…"
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article -
522
Solar syngas production via methanothermal reduction of strontium oxide
منشور في 2020"…As per the results allied with the equilibrium analysis, a temperature of 2230 K is needed for the complete conversion of SrO into Sr and CH<sub>4</sub> into a mixture of H<sub>2</sub> and CO (syngas). …"
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523
Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates
منشور في 2023"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"
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524
Aorta deformation linked to heart disease
منشور في 2015"…They found that the mechanics of the aorta were altered, with the pulsatile change in aortic diameter, distention and elasticity of the aortic walls being significantly decreased, and aortic stiffness significantly increased, in HCM patients compared to the controls. …"
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525
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
منشور في 2024"…Understanding the global burden of appendicitis is crucial for evaluating unmet needs and implementing and scaling up intervention services to reduce adverse health outcomes. …"
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article -
526
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"
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527
Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood
منشور في 2023"…The quality of gene expression data is strictly dependent on the steps used for the sample collection, extraction, preparation and sequencing. …"
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528
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
منشور في 2024"…The effect that changes in exposure parameters and examination protocol had on IQ‐scores were different depending on the IQ metric and image type. The expected positive effect that increasing IAK and decreasing tube potential should have on IQ was clearly exhibited in two IQ metrics only, the signal difference‐to‐noise‐ratio (SDNR) and the detectability index (d’), for both image types. …"
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529
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
منشور في 2021"…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …"
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530
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …"
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masterThesis -
531
Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing?
منشور في 2020"…In the absence of an effective anti-viral molecule and until the formulation of a successful vaccine, anti-inflammatory drugs might offer a complementary tool for controlling the associated complications of COVID-19 and thus decreasing the subsequent fatalities. Drug repurposing for several molecules has emerged as a rapid temporary solution for COVID-19. …"
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532
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…We determined the optimal concentration of OA needed to obtain saturating levels of triglycerides. …"
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533
Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells
منشور في 2003"…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …"
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article -
534
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…</p><h3>Methods</h3><p dir="ltr">We performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. …"
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535
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
منشور في 2022"…As the drill pipe rotational speed increased, the pressure drop decreased slightly until a critical rotatory speed was reached, thereafter, the pressure drop increased markedly. …"
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536
Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype...
منشور في 2023"…<h3>Background</h3><p dir="ltr">Skeletal muscle is the main site for insulin-dependent glucose disposal. The hyperinsulinemic euglycemic clamp (HIEC) is the gold standard for the assessment of insulin sensitivity (IS). …"
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537
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
منشور في 2013"…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …"
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538
Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species
منشور في 2022"…<p dir="ltr">The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …"
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539
Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study
منشور في 2020"…<h3>Background</h3><p dir="ltr">To contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990–2020, and forecasts for 2050.…"
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540
Effects of visual field impairment on driving
منشور في 2015"…Furthermore, the analysis needs to be complemented with an analysis which consider diagnosis and cognitive status.…"