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301
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"
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302
Increased footwear comfort is associated with improved running economy – a systematic review and meta‐analysis
منشور في 2021"…<p dir="ltr">Footwear with or without custom foot orthotics have the potential to improve comfort, but the link with running performance needs further investigation. We systematically reviewed the association of footwear comfort on running economy in recreational runners. …"
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303
Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells
منشور في 2025"…Further investigations are needed to fully elucidate the molecular mechanisms underlying these effects.…"
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304
Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing?
منشور في 2020"…In the absence of an effective anti-viral molecule and until the formulation of a successful vaccine, anti-inflammatory drugs might offer a complementary tool for controlling the associated complications of COVID-19 and thus decreasing the subsequent fatalities. Drug repurposing for several molecules has emerged as a rapid temporary solution for COVID-19. …"
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305
Solar syngas production via methanothermal reduction of strontium oxide
منشور في 2020"…As per the results allied with the equilibrium analysis, a temperature of 2230 K is needed for the complete conversion of SrO into Sr and CH<sub>4</sub> into a mixture of H<sub>2</sub> and CO (syngas). …"
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306
Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates
منشور في 2023"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"
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307
Aorta deformation linked to heart disease
منشور في 2015"…They found that the mechanics of the aorta were altered, with the pulsatile change in aortic diameter, distention and elasticity of the aortic walls being significantly decreased, and aortic stiffness significantly increased, in HCM patients compared to the controls. …"
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308
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…</p><h3>Methods</h3><p dir="ltr">We performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. …"
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309
A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
منشور في 2022"…This trend was similar for all pipe eccentricities at any inclination angles, however, the critical rotational speed at which the pressure loss started to increase was found to be dependent on both the inclination angle and eccentricity. …"
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310
Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype...
منشور في 2023"…<h3>Background</h3><p dir="ltr">Skeletal muscle is the main site for insulin-dependent glucose disposal. The hyperinsulinemic euglycemic clamp (HIEC) is the gold standard for the assessment of insulin sensitivity (IS). …"
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311
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
منشور في 2013"…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …"
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312
Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study
منشور في 2020"…<h3>Background</h3><p dir="ltr">To contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990–2020, and forecasts for 2050.…"
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313
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…We determined the optimal concentration of OA needed to obtain saturating levels of triglycerides. …"
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314
A Novel Technique for Detecting Underground Water Pipeline Leakage Using the Internet of Things
منشور في 2023"…Besides, reducing the amount of time needed to precisely detect and locate the leak is another challenge. …"
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315
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
منشور في 2023"…The upregulation of Voltage-dependent anion-selective channel protein 1 (1.9-fold), Major vault protein (1.8-fold), Bax (1.16-fold), and Cytochrome C (1.39-fold) indicate the activation of the intrinsic pathway. …"
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316
Therapeutic targeting of the TPX2/TTK network in colorectal cancer
منشور في 2023"…<h3>Background</h3><p dir="ltr">While the increased screening, changes in lifestyle, and recent advances in treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease and recurrence remains a major clinical challenge. …"
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317
Effects of visual field impairment on driving
منشور في 2015"…Furthermore, the analysis needs to be complemented with an analysis which consider diagnosis and cognitive status.…"
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318
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
منشور في 2022"…In order to control fine particles transport in porous media, the behavior itself needs to be predicted and analyzed. Which could be quite costly to do in a laboratory experiment, hence the modelling of such a behavior would be an optimum way to study. …"
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319
Immunoprofile of childhood diabetes
منشور في 2023"…In order to be functional, the CD49d integrin needs to form a heterodimer with ITGB1 protein. When transcriptomic data was interrogated, an imbalance between ITGA4/ ITGB1 was observed in all groups where CD49d showed increased expression. …"
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320
Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit
منشور في 2024"…Gentamicin dose regimen continuations, dose regimen decreases and dose regimen discontinuations were inappropriately applied in 27% (<i>n</i> = 10), 25% (<i>n</i>= 2) and 14% (<i>n</i> = 1) of the times, respectively.…"