Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Immunoprofile of childhood diabetes حسب Meritxell Espino-Guarch (15430868)

"…Associated with these findings, anti-inflammatory Treg cytokines including IL-10 were decreased in T2D patients and elevated plasma levels of IL-17, which contributes to the insulin resistance and inflammation were observed.…"

Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women حسب Vijay, Ganji

"…Vitamin D deficiency has been linked to increased adiposity and decreased bone density. It is not known if vitamin D is linked to adiposity measures and bone mass in postmenopausal Qatar women. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

LDL-C Targets in Secondary Prevention: How Low Should We Go? حسب Karim Bayoumy (3496688)

"…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …"

Examining time-to-transport decisions in Emergency Medical Services حسب Hassan Farhat (9000509)

"…As the time spent on scene increases (due to various reasons, among them: spending more time providing clinical treatment and health education because the patient decided not to go to the hospital, or the crew spending more time convincing the patient to go to the hospital by explaining the potential complications of their condition and the potential outcomes of a refusal to go to hospital), the probability of transporting the patient decreases. This trend suggests that extended time could adversely affect patient care if they eventually need to recall for an ambulance. …"

Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system حسب Mohammadreza, Gholami

"…Also, by integrating BESS, the contribution of RESs to outage hours and lost energy is effectively decreased from 89.41% and 87.41% to 32.69% and 28.94% respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim Al-Fahdawi (17844209)

"…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …"

Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study حسب Adnan Qamar (14421759)

"…VC and TC increased by increasing the NFs concentration and decreased by increasing the operating temperature. …"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…The complex and dynamic interactions of the secreted cytokines, chemokines, growth factors, and their receptors mediate chronic inflammation and immunosuppressive TME favoring tumor progression, metastasis, and decreased response to therapy. The molecular changes in the TME are used as biological markers for diagnosis, prognosis, and response to treatment in patients. …"

The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global... حسب Farin Kamangar (63964)

"…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …"

Tranexamic Acid Application in Facial Aesthetic Surgery: An Umbrella Review حسب Mohamed Badie Ahmed (10223510)

"…While in the case of septorhinoplasty, 3 studies revealed that TXA use decreased BLV. Moreover, in the case of rhytidectomy, 3 out of 6 systematic reviews showed reduction in BLV, while 2 reported reductions in DOS. …"

Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta... حسب Mohammed M. Al-Humaiqani (18325554)

"…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. Achieving resilience objectives in the built environment is challenging and requires the collaboration of all relevant sectors and professionals. …"

Visible Light Photocatalytic Activity of Ag/WO₃ Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark حسب Maha Matalkeh (17148358)

"…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. Photocatalytic analysis at different concentrations of 1% Ag/WO₃ under visible light indicated a high degradation efficiency. …"

Epidemiological and clinical characteristics of fall-related injuries: a retrospective study حسب Ahammed Mekkodathil (4578838)

"…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …"

Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial) حسب Nissar Shaikh (11659441)

"…The proposed theory behind that was that fentanyl decreased the rate of spontaneous respiratory rate, diminished the brain stem chemoreceptor response to hypoxia and hypercarbia, in addition to exhibiting a modulating effect on the brain stem. …"

Prediction of critical total drawdown in sand production from gas wells: Machine learning approach حسب Fahd Saeed Alakbari (10701871)

"…The RSM correlation decreased the average absolute percent relative error (AAPRE) by 12.7% compared to all published correlations' AAPRE of 22.6%–30.4%. …"

Recyclable polyaspartate-coated magnetic nanoparticles for sustainable control of calcite and barite scales in oilfield operations حسب Abdelrahman T. Abdelaal (14674629)

"…<p dir="ltr">Scale formation is a major challenge in hydrocarbon production, leading to decreased efficiency, equipment damage, and increased operational costs. …"

Clinical and Biochemical Analysis of Glutamate-Cysteine Ligase Deficiency Presented with Late-Onset Spinocerebellar Ataxia and Hemolytic Anemia حسب Mohammed Al-Hatou (22225603)

"…Magnetic resonance imaging of the head and cervical spine showed global cerebellar atrophy with widened folia and decreased diameter of the upper cervical spine. Blood workup revealed hemolytic anemia with genetic testing confirmed a homozygous variant, c.514 T>A in exon 4 of the GCLC gene, resulting in Ser172Thr (TCC>ACC). …"

Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO₂ with Exceptional Textural Properties and Superior Adsorption Kinetics حسب Yahia H. Ahmad (14340210)

"…The average particle size ranged between 9.7 and 27.5 nm and it decreased with increasing the Mo content. Furthermore, Mo-TiO₂ revealed mesoporous architectures with a high surface area ranging between 170 and 260 m² g⁻¹, which is superior compared to previously reported Mo-doped TiO₂. …"