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221
A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants
منشور في 2021"…Therefore, strategies tailored to cultures and socio-psychological factors need to be developed to reduce vaccine hesitancy and aid informed decision-making.…"
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222
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co...
منشور في 2024"…Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). …"
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223
Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
منشور في 2025"…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. …"
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224
Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
منشور في 2019"…These observations support the need to consider anti-NRP-1 as a potential targeted therapy for breast cancer patients who are identified with high NRP-1 levels. …"
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225
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
منشور في 2021"…<h3>Background</h3><p dir="ltr">Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. There is an urgent need for disease-modifying therapies for Parkinson’s disease, but drug discovery is challenged by lack of in vivo models that recapitulate early stages of neurodegeneration. …"
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226
Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
منشور في 2022"…Female sex (61.5 % vs. 41.3 %, p = 0.019), hypoxemia (90 % vs. 59.2 %, p < 0.001), massive PE features (89.7 % vs. 30.1 %, p < 0.001), associated chronic kidney disease (CKD) (10.3 % vs. 1.4 %, p = 0.002), and the need for mechanical ventilation (28.2 % vs. 13.1 %, p = 0.02) were significantly associated with increased mortality. …"
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227
The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
منشور في 2020"…The results reinforce the need for continued and improved policy, prevention and research efforts, with a focus on low- and middle-income countries.…"
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228
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and family planning and support. …"
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229
Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019
منشور في 2021"…Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. …"
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230
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
منشور في 2021"…Liquid (bounce fraction; BF < 0.2) at RH > 80 % and nonliquid behaviour (BF > 0.8) at RH < 30 % were observed, with a liquid-to-nonliquid transition with decreasing RH between 30 % and 80 %. This RH-dependent phase behaviour (RH<sub>BF=0.2, 0.5, 0.8</sub>) increased towards a maximum, with an increasing organic–inorganic mass ratio (MR<sub>org</sub><sub>/inorg</sub>) during SOA formation evolution in all investigated VOC systems. …"
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231
The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review
منشور في 2024"…Spirulina was effective in reducing body weight, body mass index, and waist circumference, with a potential dose-dependent effect. It also decreased interleukin 6, an important biomarker of body inflammation, by inhibiting NADPH oxidase enzyme, and lowering insulin resistance. spirulina supplementation also reduced triglycerides, low-density lipoprotein cholesterol, and increased high-density lipoprotein cholesterol. …"
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232
A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems
منشور في 2020"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"
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233
Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis
منشور في 2024"…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …"
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234
Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
منشور في 2020"…Interpretation Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. By highlighting areas with successful approaches or in need of targeted interventions, our estimates can enable precision public health to effectively progress towards universal access to safe water and sanitation. …"
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235
Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac
منشور في 2023"…The spectral information obtained for the photochemical reaction of DCF in a set of neat solvents demonstrates that the photoconversion reaction rate of DCF is not only medium polarity dependent but also hydrogen-bonding dependent. The solvent effects were qualitatively and quantitatively assessed employing various solvatochromic models, including multi-parameter linear regression analysis (MLRA). …"
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236
Engineering Novel Single-chain Variable Fragments for Therapeutic and Diagnostic Approaches in Parkinson's Disease
منشور في 2019"…An <i>in vitro</i> α-synuclein aggregation assay revealed that the scFvs inhibit the seeding of α-synuclein aggregation in a time-dependent manner, monitored by Th-S assay. Furthermore, the scFvs decreased α-synuclein seed-induced toxicity in a cell model of PD. …"
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237
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
منشور في 2020"…Mechanically stretching the RPV significantly decreased APN protein expression after 24 hours and APN mRNA expression in a time-dependent manner in VSMCs. …"
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238
Nonlinear effects in locally resonant nanostrip phononic metasurface at GHz frequencies
منشور في 2021"…Due to the nonlinearity, the resonance frequency of the device decreases with the increase in stimulation power. The underlying mechanism of the nonlinearity is found to be the power-dependent coupling of the adjacent nanostrips. …"
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239
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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240
Electrically conductive hybrid organic crystals as flexible optical waveguides
منشور في 2022"…In cyclic operation mode, their conductivity decreases less than 1% after 10,000 thermal cycles. …"
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