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241
Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
منشور في 2020"…In vitro studies indicated scFvs inhibit the seeding of α-syn aggregation in a time-dependent manner, decreased α-syn seed-induced toxicity in a cell model of PD, and reduced the production of insoluble α-syn phosphorylated at Ser-129 (pS129-α-syn). …"
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242
Receivers location privacy in avionic crowdsourced networks: Issues and countermeasures
منشور في 2021"…<p dir="ltr">The lack of message encryption characterizing wireless avionic protocols, including Automatic Dependent Surveillance - Broadcast (ADS-B), recently favored the rise of a few communities that, gathering data collected by receivers at the ground or in space, offer advanced services, while at the same time releasing the cited data to the public.…"
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243
Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study
منشور في 2023"…The viscosity (VC) and thermal conductivity (TC) of NFs exhibited a strong dependence on the operating temperature and NFs concentration. …"
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244
Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study
منشور في 2021"…The nanopores absorbed up to 28 and 24 molecules of CH<sub>4</sub> and CO<sub>2,</sub> respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å<sup>2</sup> for each. …"
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245
Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
منشور في 2021"…Vitamin D deficiency was associated with decreased CD80 and IFN-γ in PCOS and IL-12 in both groups (p<0.05). …"
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246
Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
منشور في 2023"…In contrast, increasing the crosslinker content decreases the swelling ratio and increases the gel strength. …"
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247
Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture
منشور في 2018"…The presence of a shell decreases the activation energy, which is associated with the elastic properties of the core. …"
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248
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
منشور في 2013"…Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. Treatment of diabetic mice with baicalein significantly decreased retinal HETE, ICAM-1, VCAM-1, IL-6, ROS generation, and NOX2 expression. …"
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249
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …"
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250
Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer
منشور في 2023"…Although, death rates due to BC have consistently decreased over time, TNBC still poses a challenge due to its poor prognosis, high rates of relapse and resistance to chemotherapy. …"
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251
Graph-Guided Regularized Regression of Pacific Ocean Climate Variables to Increase Predictive Skill of Southwestern U.S. Winter Precipitation
منشور في 2021"…Recently, promising data-driven approaches have been proposed, but they often suffer from overparameterization and overfitting due to the short observational record, and they often do not account for spatiotemporal dependencies among covariates (i.e., predictors such as sea surface temperatures). …"
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252
Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity
منشور في 2021"…At hypoglycemia, however, four proteins changed in controls from baseline [Thrombospondin-1 (p < 0.014), platelet factor-4 (p < 0.01), Platelet basic protein (p < 0.008), and Vitamin K-dependent protein-C (p < 0.00003)], and one protein changed in T2D [Vitamin K-dependent protein-C, (p < 0.0002)].…"
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253
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
منشور في 2022"…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …"
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254
Heat Transfer Coefficient Estimation of Falling Film for Horizontal Tube Multi-Effect Desalination Evaporator Using CFD
منشور في 2021"…Furthermore, the higher operating temperature limit should be increased instead of decreasing operating temperature for improved heat transfer performance.…"
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255
Optimization of Community Integrated Energy System for the State of Qatar Towards Sustainable Development
منشور في 2025"…It supports integrating clean technologies while addressing local energy needs. The findings provide a pathway for sustainable urban planning and energy system design, reinforcing the significance of integrated energy solutions in achieving national targets.…"
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256
Sulfobetaine-based polydisulfides with tunable upper critical solution temperature (UCST) in water alcohols mixture, depolymerization kinetics and surface wettability
منشور في 2021"…The regeneration of monomers by depolymerization was tunable by temperature and sunlight. A thickness dependence on surface wettability was observed on wafers covalently modified with polydisulfides. …"
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257
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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258
Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models
منشور في 2020"…An extended dataset will enable a means to independently validate the defined models and test other modelling approaches. …"
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259
Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
منشور في 2018"…Chronic sodium selenate treatment efficiently reversed hippocampal-dependent learning and memory impairments, and behavior- and neuropsychiatric-like symptoms in old female 3xTg-AD mice. …"
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260
Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation
منشور في 2024"…Qualitative description of the experimental results is given through bond distance-dependent total energy calculations and structural and electronic structure analysis within density functional theory. …"