Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose حسب Roberta Giordo (299595)

"…Treatment of HRECs with HG increased intracellular ROS levels and promoted phenotype shifting towards EndMT, evidenced by decreased expression of endothelial markers concomitant with increased expression of mesenchymal ones. …"

Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 حسب Letourneau, Ian D

"…Understanding the global burden of appendicitis is crucial for evaluating unmet needs and implementing and scaling up intervention services to reduce adverse health outcomes. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Determining the influencing factors in the residential rooftop solar photovoltaic systems adoption: Evidence from a survey in Qatar حسب Omar F. Alrawi (19418938)

"…<p>Renewable energy sources have developed rapidly, decreased in cost, and proven to have the potential to limit global warming. …"

Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application حسب Lama Soubra (11666333)

"…Patient satisfaction from the provided interventions/services was determined by means of an overall rating. The correlation between practiced roles and patient satisfaction with received interventions/services was determined.…"

COVID-19 biomarkers for severity mapped to polycystic ovary syndrome حسب Abu Saleh Md Moin (6189512)

"…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"

Increased footwear comfort is associated with improved running economy – a systematic review and meta‐analysis حسب K. Van Alsenoy (21259700)

"…<p dir="ltr">Footwear with or without custom foot orthotics have the potential to improve comfort, but the link with running performance needs further investigation. We systematically reviewed the association of footwear comfort on running economy in recreational runners. …"

Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells حسب Hafsa Madni (22674428)

"…Further investigations are needed to fully elucidate the molecular mechanisms underlying these effects.…"

Thalidomide-Revisited: Are COVID-19 Patients Going to Be the Latest Victims of Yet Another Theoretical Drug-Repurposing? حسب Athar Khalil (5906330)

"…In the absence of an effective anti-viral molecule and until the formulation of a successful vaccine, anti-inflammatory drugs might offer a complementary tool for controlling the associated complications of COVID-19 and thus decreasing the subsequent fatalities. Drug repurposing for several molecules has emerged as a rapid temporary solution for COVID-19. …"

Solar syngas production via methanothermal reduction of strontium oxide حسب Rahul R. Bhosale (6467102)

"…As per the results allied with the equilibrium analysis, a temperature of 2230 K is needed for the complete conversion of SrO into Sr and CH₄ into a mixture of H₂ and CO (syngas). …"

Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates حسب Fariha Niaz (14778319)

"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"

Aorta deformation linked to heart disease حسب Nature Research (16552612)

"…They found that the mechanics of the aorta were altered, with the pulsatile change in aortic diameter, distention and elasticity of the aortic walls being significantly decreased, and aortic stiffness significantly increased, in HCM patients compared to the controls. …"

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Anas Hamad (9545771)

"…The Q-OHEP also recommended implementing a forecast system using treatment center data based on the supply/demand of formulary oncology drugs to detect treatment patterns, estimate needs, expedite procurement, and prevent shortages/delays. …"

Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems حسب Local Burden of Disease HIV Collaborators (13279180)

"…</p><h3>Methods</h3><p dir="ltr">We performed an ecological study using VR data ranging from 2000 to 2017, dependent on individual country data availability. …"

A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters حسب Abdelrahman M. Awad (16932519)

"…As the drill pipe rotational speed increased, the pressure drop decreased slightly until a critical rotatory speed was reached, thereafter, the pressure drop increased markedly. …"

Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype... حسب Ilham Bettahi (363910)

"…<h3>Background</h3><p dir="ltr">Skeletal muscle is the main site for insulin-dependent glucose disposal. The hyperinsulinemic euglycemic clamp (HIEC) is the gold standard for the assessment of insulin sensitivity (IS). …"

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity حسب Mohamed Abu-Farha (18535590)

"…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …"

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study حسب Rupert Bourne (603842)

"…<h3>Background</h3><p dir="ltr">To contribute to the WHO initiative, VISION 2020: The Right to Sight, an assessment of global vision impairment in 2020 and temporal change is needed. We aimed to extensively update estimates of global vision loss burden, presenting estimates for 2020, temporal change over three decades between 1990–2020, and forecasts for 2050.…"

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…We determined the optimal concentration of OA needed to obtain saturating levels of triglycerides. …"

Factors Associated with Meeting Current Recommendation for Physical Activity in Scottish Adults with Diabetes حسب Ahmad Salman (3173418)

"…Implementation of health promotion programs that target the identified determinants is needed to improve the recommended levels of physical activity among adults with diabetes.…"