Deletion of the Candida albicans PIR32 Results in Increased Virulence, Stress Response, and Upregulation of Cell Wall Chitin Deposition حسب Bahnan, Wael

"…As such, we measured cell wall chitin deposition and found a twofold increase in the mutant, possibly explaining the above-observed phenotypes.…"
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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system حسب Frank Schmidt (207186)

Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans حسب Mahmoud Izadi (12899508)

"…More recently, mutations in the tryptophanyl-tRNA synthetase 1 (WARS1) have been linked to various human diseases, from intellectual disability to various types of cancer. …"

Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>) حسب Albandari Bin-Ammar (16381128)

"…A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …"

Impacts of climate change on the global spread and habitat suitability of <i>Coxiella burnetii</i>: Future projections and public health implications حسب Abdallah Falah Mohammad Aldwekat (22457821)

"…<h3>Introduction</h3><p dir="ltr"><i><u>Coxiella burnetii</u></i><i><u>,</u></i> an intracellular zoonotic bacterium, affectsing various livestock and <u>wildlife</u> species and poses significant risks to human health. …"

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells حسب Shebaby, Wassim N.

"…Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …"
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Photoemission study of the electronic structure of LaFeAsO 1-xFx and LaFePO1-xFx حسب Malaeb, Walid

"…Also, in going from LaFeAsO1-xF x to LaFePO1-xFx, the near-EF intensity increases reflecting the weakening of electron correlation.…"
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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase حسب Marta Cecchi (21363581)

Rodent-borne zoonoses in Qatar: A possible One-Health framework for the intervention of future epidemic حسب Md. Mazharul Islam (9082853)

"…<p>The increasing frequency of spillover of zoonotic pathogens from animals to humans in recent years highlights a need to develop a more comprehensive framework to investigate and prevent pathogens of animal origin, including rodents. …"

One Dimensional Seismic Site Response Analysis of United Arab Emirates حسب Eltayeb, Ahmed Mohamed Zaroug

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An optimization approach to increasing sustainability and enhancing resilience against environmental constraints in LNG supply chains: A Qatar case study حسب Sara Al-Haidous (18095368)

Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis حسب Ahmed Fouad Algendy (18102706)

"…The risk of SHEA (Adjusted Odds Ratio AOR 6.74, p=0.002), falls (AOR 1.43, p=0.003), fractures (AOR 1.43, p=0.01), CVEA (AOR 1.66, p< 0.001), recurrent ED admission (AOR 1.39, p=0.002) were significantly higher. …"

The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues حسب Naushad Ahmad Khan (6406973)

"…<p dir="ltr">The emergence of highly mutated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant Omicron (B.1.1.529) has ushered panic responses around the world due to its contagious and vaccine escape mutations. …"

Long-term increases in vasorelaxation and blood flow to the pregnant sheep uterus following local delivery of adenovirus VEGF to uterine arterie حسب Abi-Nader, K

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Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy حسب Nassiba Taib (14557385)

"…Interestingly, in the metastatic 1872 Col cells treated with DAC, the expression of both PD-L1 and NY-ESO-1 was increased tenfold (*p = 0.0128) and fivefold (***p < 0.0001), respectively.…"

ABCB1 (P-glycoprotein) and blood-brain barrier حسب Milane, Aline

"…Furthermore, ABCB1 expression and/or functionality may modify drug efficacity or increase central adverse events. …"
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Stress granules counteract senescence by sequestration of PAI‐1 حسب Amr Omer (18629374)

"…PAI‐1 localization to SGs increases the translocation of cyclin D1 to the nucleus, promotes RB phosphorylation, and maintains a proliferative, non‐senescent state. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…Evidence supports a role for vascular aging in the development of hypertension involving an impairment in endothelial function together with an alteration in vascular smooth muscle cells (VSMCs) calcium homeostasis leading to increased myogenic tone. Changes in free intracellular calcium levels ([Ca²⁺]_<em>i</em>) are mediated either by the influx of Ca²⁺ from the extracellular space or release of Ca²⁺ from intracellular stores, mainly the sarcoplasmic reticulum (SR). …"

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"

Novel Thermo-Halotolerant Bacteria <i>Bacillus cabrialesii </i>Native to Qatar Desert: Enhancing Seedlings’ Growth, Halotolerance, and Antifungal Defense in Tomato حسب Fatma Masmoudi (16819554)

"…</i> cerasiforme and promote seeds germination and seedlings growth under saline conditions. …"