Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Effects on in vivo ectopic bone formation were assessed by implanting hMSC mixed with hydroxyapatite-tricalcium phosphate granules subcutaneously in 8-week-old female nude mice, and the amount of bone formed was assessed using quantitative histology. Results. BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …”

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort by Fatima Qafoud (14778571)

“…<h3>Background</h3><p dir="ltr">Resting electrocardiogram (ECG) is a valuable non-invasive diagnostic tool used in clinical medicine to assess the electrical activity of the heart while the patient is resting. …”

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Amira Othman (380131)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: PLoS ONE<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1371/journal.pone.0057254" target="_blank">https://dx.doi.org/10.1371/journal.pone.0057254</a></p><p dir="ltr">Additional institutions affiliated with: College of Science - QU (1977-2004/2005), College of Arts and Sciences - QU (2004/05-2016).…”

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties by Jelena Eric (21015107)

“…Tooth shade and enamel microhardness were evaluated using a digital spectrophotometer and a Vickers tester, respectively, at different time intervals after treatment. …”

Basin of Attraction through Invariant Curves and Dominant Functions by Alsharawi, Ziyad

“…We study a second-order difference equation of the form z<inf>n+1</inf> = z<inf>n</inf> F (z<inf>n-1</inf>) + h, where both F (z) and z F (z) are decreasing. …”
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Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming by Mohamed, Assem T.

“…In addition, the presence of noble metals at the Ni surface afforded a high density of adsorbed oxygen species, which enhanced coke gasification and consequently decreased the extent of deactivation of the catalysts by coke formation. …”
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Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …”

Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) by Khaled F. Alkaraki (22051967)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: GeoJournal<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10708-024-11187-3" target="_blank">https://dx.doi.org/10.1007/s10708-024-11187-3</a></p>…”

Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth by Felipe, Torquato

“…In turn, multivariate analyses showed a slight structure among platforms with different ages. …”
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Spectrofluorometric investigations on the solvent effects on the photocyclization reaction of diclofenac by Abdulilah Dawoud, Bani-Yaseen

“…The spectral information obtained for the photochemical reaction of DCF in a set of neat solvents demonstrates that the photoconversion reaction rate of DCF is not only medium polarity dependent but also hydrogen-bonding dependent. …”
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Effects of UV Radiation on Germination, Growth, Chlorophyll Content, and Fresh and Dry Weights of Brassica rapa L. and Eruca sativa L. by Hussan Ara Begum (17542320)

“…The source of UV light was a UV box having a UV Tube. The UV exposure on the seeds reduced the germination percentage in both species. …”

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…However, 4-hours post-hypoglycemia, sNRP1, VEGF and ADAM9 were elevated in T2D(p<0.05). SEMA3A was not different at baseline; at hypoglycemia, SEMA3A decreased in controls only. …”

Frugal innovation for sustainable rural development by Mokter, Hossain

“…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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Effects of financial turmoil on financial integration and risk premia in emerging markets by Boubakri, Salem

“…Accordingly, we estimate a variant of the International Asset Pricing Model developed by Carrieri et al. (2007), allowing for time-varying stock market integration, in which we include the foreign currency risk. …”
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Institutional development and the dowry death curve across states in India by Austin M. Mitchell (14778793)

“…Women are increasingly exploited and murdered over dowry as incomes increase from a low level, but fewer deaths occur as incomes increase from a high level. …”

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming by Yahia H. Ahmad (14340210)

“…In addition, the presence of noble metals at the Ni surface afforded a high density of adsorbed oxygen species, which enhanced coke gasification and consequently decreased the extent of deactivation of the catalysts by coke formation. …”

Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties by Slimani, Ahmed

“…The XRD results show that the 850 °C is the best calcination temperature, where the NBT-6BT ceramic had the largest crystallite size with a dense sample, 96% of the theoretical value. However, the density decreased significantly with increasing the calcination temperature above 850 °C due to the secondary phase formation. …”
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Electrically conductive hybrid organic crystals as flexible optical waveguides by Li, Liang

“…Hybrid materials capitalize on the properties of individual materials to attain a specific combination of performance assets that is not available with the individual components alone. …”
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Assessing Intra-Arab Trade Integration and Potential: Evidence from the Stochastic Frontier Gravity Model by Ebaidalla M. Ebaidalla (16960008)

“…The results also reveal that the influence of “behind the border” constraints on trade flows between Arab countries has been decreasing over time. Moreover, the efficiency scores of intra-Arab trade indicate a relatively low degree of trade integration among Arab countries.…”