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Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…<h3>Background</h3><p dir="ltr">Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. There is an urgent need for disease-modifying therapies for Parkinson’s disease, but drug discovery is challenged by lack of in vivo models that recapitulate early stages of neurodegeneration. …”
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Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
Published 2022“…Female sex (61.5 % vs. 41.3 %, p = 0.019), hypoxemia (90 % vs. 59.2 %, p < 0.001), massive PE features (89.7 % vs. 30.1 %, p < 0.001), associated chronic kidney disease (CKD) (10.3 % vs. 1.4 %, p = 0.002), and the need for mechanical ventilation (28.2 % vs. 13.1 %, p = 0.02) were significantly associated with increased mortality. …”
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A systematic review on sequence-to-sequence learning with neural network and its models
Published 2021“…The evidence we adopted in conducting this survey included utilizing the examination inquiries or research questions to determine keywords, which were used to search for bits of peer-reviewed papers, articles, or books at scholastic directories. …”
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Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai
Published 2017“…The author further noted that cultural diversity has formed a paramount issue in business arena that need to be investigated to pave a clear way in order to accommodate people from various backgrounds. …”
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Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery
Published 2010Get full text
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Bulk passivation of perovskite films utilizing halide anion ionic liquids
Published 2023Get full text
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TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
Published 2019Get full text
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally.…”