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521
Dicarbonyl stress, protein glycation and the unfolded protein response
Published 2022“…An effective strategy to counter increased MG is inducing increased expression of glyoxalase-1 (Glo1). An optimized inducer of Glo1 expression, trans-resveratrol and hesperetin combination, normalized increased MG concentration, corrected insulin resistance and decreased low grade inflammation in overweight and obese subjects. …”
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522
Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity
Published 2021“…In conclusion, Celsr3 is required for PCs maturation and regulates postsynaptic LTP and LTD through Wnt5a/cAMP and mGluR1/PKCα signaling respectively.</p><h2>Other Information</h2> <p> Published in: iScience<br> License: <a href="http://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank">http://creativecommons.org/licenses/by-nc-nd/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.isci.2021.102812" target="_blank">https://dx.doi.org/10.1016/j.isci.2021.102812</a></p>…”
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523
Improving the performance of a commercial absorption cooling system by using ejector: A theoretical study
Published 2023“…It was found that the increase in the ambient temperature not only increased the activation temperature, but it also decreased the COP and increased the circulation ratio (CR). …”
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524
Crunching the numbers of food poisoning in Qatar
Published 2016“…<p>Salmonellosis is a common type of food poisoning caused by <i>Salmonella</i> bacteria. It affects tens of millions and kills more than 100,000 people every year worldwide. …”
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525
Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
Published 2021“…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…”
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526
Solar syngas production via methanothermal reduction of strontium oxide
Published 2020“…The process efficiency is also enhanced from 24.5% to 38.7% due to the escalation in the CH<sub>4</sub>/SrO ratio from 0.1 to 1. Application of heat recuperation considerably decreased the requirement of solar energy input, and hence the process efficiency is further amplified. …”
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527
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
Published 2020“…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”
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528
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…ResultsShade analysis revealed that, in the short term, HP treatment significantly increased lightness and Hue and decreased chroma compared to DW (p < 0.05); however, 1 week after treatment some of the initial gains in tooth lightness were partially lost. …”
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529
Synthesis of lithium manganese oxide nanocomposites using microwave‐assisted chemical precipitation technique and their performance evaluation in lithium‐ion batteries
Published 2023“…Cycling efficiency is also improved, with LMO-CNTs and LMO-GNPs having an initial capacity of 124 and 127 mAhg<sup>−1</sup> decreasing to 112 and 114 mAhg<sup>−1</sup>, respectively, after 50 cycles. …”
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530
Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete
Published 2020“…The proposed concrete mixture, which has 100% of expanded perlite aggregate, has a unit weight of 1703 kg/m3 and achieved reduction percentage of thermal conductivity around 62% (1.81 to 0.69 W·m−1·K−1) and a compressive strength of 42 MPa at 28 days; and thus is ideal for structural applications with enhanced properties.…”
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531
Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines
Published 2020“…In fact, by the introduction of nanotubes the mobility of curing moieties decreased resulting in some deviation of experimental cure rate values from the predicted values obtained using <i>KAS</i> and <i>Friedman</i> methods.…”
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532
Prediction of critical total drawdown in sand production from gas wells: Machine learning approach
Published 2023“…The SVM model has shown the lowest AAPRE of 6.1%, with the highest <i>R</i> of 0.995. The effects of all independent variables on the CTD are displayed in three-dimensional plots and showed significant interactions.…”
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533
Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index
Published 2021“…It is reported that PCOS subjects show marked platelet dysfunction and decreased plasma fibrinolytic activity, resulting in a prothrombotic state. …”
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534
Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
Published 2022“…Significant differences included various frequency domain and nonlinear HRV parameters, particularly between first and fourth HN quintiles with p values < 0.001 for recurrence plot analysis (RPA), detrended fluctuation analysis (DFA) a1 and Poincaré plot ratio SD1/SD2. The results revealed non-monotonic relationships between measures of HRV and HN concentration. …”
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535
Modulation of gut microbiota: The effects of a fruits and vegetables supplement
Published 2022“…The gut microbiome composition, measured by 16S rDNA sequencing, showed no difference in both alpha and beta diversities, whereas the LEfse analysis revealed a microbial shift after the treatment, with a decreased abundance of the genus <i>Ruminococcus</i> from the Lachnospiraceae family (<i>p</i> = 0.009), and the unclassified genus from the family Erysipelotrichaceae (UC36, <i>p</i> = 0.003) in the FVS group compared with the PLA group (confirmed by SIAMCAT analysis, AUC = 74.1%). …”
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536
Genome-wide association study and meta-analysis of phytosterols identifies a novel locus for serum levels of campesterol
Published 2024“…The meta-analysis replicated most of the reported variants, and our study provided significant support for the association of variants in <i>SCARB1</i> and <i>ABO</i> with sitosterolemia. …”
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537
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…The IC<sub>50</sub> values were found to be in the micromolar to submicromolar range. The <i>K</i><sub><em>i</em></sub> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”
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538
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
Published 2021“…Expression of FSCN1<sup>high</sup> (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1<sup>CON</sup> vs. …”
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539
Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient
Published 2023“…</p><h3>Hypothesis</h3><p dir="ltr">1) LRBA deficiency in the patient leads to decreased surface CTLA-4 expression level and therefore immune mediated type 1 diabetes mellitus. 2) LRBA protein may be involved in the insulin biosynthesis and secretion in β-cells.…”
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540
Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability
Published 2021“…To reduce the ripple in the input current with simultaneous decreasing the input current ripple, a novel current fed interleaved high gain converter is proposed by utilizing the interleaved front-end structure and Cockcroft Walton (CW)-Voltage Multiplier (VM). …”