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901
Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk
Published 2015“…Moreover, it also shows the effect of smoking-gene interaction on CAD risk, where the CYP1A1 MspI polymorphism revealed a decreased risk in current smokers.…”
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902
High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…Most of these TSH-LFIAs are designed for qualitative measurements (i.e., if TSH values > 5, or >15 IU/L) and as screening tests for primary hypothyroidism in children and adults. …”
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903
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…Stretching the RPV for 10 minutes significantly decreased phosphorylation of LKB1, AMPK, and eNOS, while APN significantly increased p-LKB1, p-AMPK, and p-eNOS in stretched vessels. …”
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904
Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
Published 2021“…A total of 1,768 studies have been reviewed, and 142 studies were found eligible and considered in the analysis. …”
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905
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
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906
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907
Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published 2018“…Subcutaneous adipose tissue (SAT) and blood samples were collected from obese adults with and without diabetes (<i>n</i> = 138 and <i>n</i> = 92, respectively, at baseline; <i>n</i> = 43 for both groups after 3 months of physical exercise). …”
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908
Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP)
Published 2023“…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. However, the cancer-related burden on patients, healthcare systems, and the economy is expected to expand; thus, cancer remains a significant public healthcare issue in Qatar. …”
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909
Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma
Published 2008“…PDGF-BB treatment of cells enhanced migration and proliferation after 24 hr; increased PDGFRβ, PI3K, Akt and Erk1/2 activity, decreased PTEN activation and transactivated EGFR. …”
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910
Microstructure and Compressive Behavior of Al–Y<sub>2</sub>O<sub>3</sub> Nanocomposites Prepared by Microwave-Assisted Mechanical Alloying
Published 2019“…The mechanical properties of the Al–Y<sub>2</sub>O<sub>3</sub> nanocomposites increased as the addition of yttria reached to 1.5 vol. % and thereafter decreased. The microhardness first increased from 38 Hv to 81 Hv, and then decreased to 74 ± 4 Hv for 1.5 vol. % yttria. …”
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911
Nonlinearities in the response of real GDP to oil price shocks
Published 2017“…I follow Kilian and Vigfusson (2011a) and conduct a test of symmetry. …”
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912
How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly
Published 2024“…TKA showed no variation across groups, while LLA decreased with advancing LS risk stage. Except for L1–L2 and L5–S1, lumbar disc height (LDH) decreased with higher LS risk stages. …”
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913
The impact of scoliosis surgery on pulmonary function in spinal muscular atrophy: a systematic review
Published 2022“…Given the available evidence, the following GRADE C recommendations were made: (1) surgery is most often associated with decreases in pulmonary function; (2) the impact of surgery on pulmonary function is variable, but does not improve over pre-operative baseline; (3) surgery may result in a decreased rate of decline in pulmonary function post-operatively. …”
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914
Using B<sub>4</sub>C Nanoparticles to Enhance Thermal and Mechanical Response of Aluminum
Published 2017“…Mechanical characterization results revealed that hardness, elastic modulus, compression, and tensile strengths increased whereas ductility decreases with increasing B<sub>4</sub>C content. Al-1.0 vol. % B<sub>4</sub>C nanocomposite exhibited best hardness (135.56 Hv), Young’s modulus (88.63 GPa), and compression/tensile strength (524.67/194.41 MPa) among the materials investigated. …”
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915
The effect of the local inertial term on the fluid flow in channels partially filled with porous material
Published 2001“…It is found that the effect of the local inertial term on the channel hydrodynamics behavior is insignificant when Da<1×10−6, over the entire range of 0.1<μR<10, 0<A<104, and for all porous substrate thicknesses. …”
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916
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …”
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917
Chemical and microbiological investigations of metal ion interaction with norfloxacin
Published 1992“…The ratios were NFX:AL3+, 2:1 and 3:1 for the NFX:Mg2+ complex. The formation of a complex with Al3+ enhanced the water solubility of the drug. …”
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918
Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar
Published 2024“…</p><h3>Results</h3><p dir="ltr">The benefit-to-cost ratio was 640, representing a benefit of 1,017 QAR generated for each 1 QAR invested in the ASP service. …”
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919
An empirical study on measuring operating efficiency and revenue of real estate assets in the UAE using data envelopment analysis
Published 2022“…Likewise, on average, the inefficient buildings are 60% relatively less efficient in insurance. Result also shows that 95% of the building assets in the sample are by and large operating at decreasing returns to scale. …”
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920
ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder
Published 2017“…We also demonstrate that <i>ACTB</i> haploinsufficiency leads to reduced cell proliferation, altered expression of cell-cycle genes, and decreased amounts of nuclear, but not cytoplasmic, β-actin. …”