SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby (3756112)

“…The IC₅₀ values were found to be in the micromolar to submicromolar range. The <i>K</i>_<em>i</em> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…Expression of FSCN1^high (identified in BRCA dataset from TCGA) in conjunction with elevated expression of the top 10 upregulated or decreased expression of the top 10 downregulated genes (identified in our FSCN1^CON vs. …”

Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient by Iman Hawari (12561958)

“…</p><h3>Hypothesis</h3><p dir="ltr">1) LRBA deficiency in the patient leads to decreased surface CTLA-4 expression level and therefore immune mediated type 1 diabetes mellitus. 2) LRBA protein may be involved in the insulin biosynthesis and secretion in β-cells.…”

Topical Vancomycin for Prevention of Surgical Site Infection after Craniotomy: Meta-analysis and Systematic Literature Review by Ahmed Saleh (3150639)

“…Meta-analysis showed that topical vancomycin decreased incidence of cSSIs (OR 0.13; 95% confidence interval 0.04–0.43).…”

Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications by Tooba Yasin (19131382)

“…Similarly, increasing ZiF-8 improved the antibacterial activities against Gram-positive (<i>Staphylococcus aureus</i> (<i>S. aureus</i>)) and Gram-negative (<i>Escherichia coli</i> (<i>E. coli</i>)), which will provide an extra protective antibacterial shield to support wound healing. …”

Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors by Yu Wang (12152)

“…Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …”

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project by Mariam Al-Mutawa (18505317)

“…implementation, from 0.9/1,000 patient-days [Q3 2020 – Q4 2021] to 0.31/1,000 per patient-days [Q1 2022 – Q2 2023] (Figure 1). …”

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20... by Sudabeh Alatab (11257335)

“…The total YLDs attributed to IBD almost doubled over the study period, from 0·56 million (0·39–0·77) in 1990 to 1·02 million (0·71–1·38) in 2017. The age-standardised rate of DALYs decreased from 26·5 (21·0–33·0) per 100 000 population in 1990 to 23·2 (19·1–27·8) per 100 000 population in 2017. …”

Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor by Ebrahimi, Parisa

“…Furthermore, the hydrogen to carbon monoxide (H₂/CO) molar ratio peaked at over 1.1 at 650 °C, dropped to approximately 0.76 at 750 °C, and then rose back to 0.97 at 950 °C. …”
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Life cycle assessment and sustainability enhancement of closed-loop carbon dioxide enhanced oil recovery: Field-scale evaluation in Qatar’s Dukhan Reservoir by Razan Sawaly (19170910)

“…Global warming potential (GWP100) decreased from 2.00 × 10¹⁰ kg CO₂-eq in Year 1 to 1.20 × 10⁹ kg CO₂-eq in Year 21, with a 16% reduction observed in Year 1 under the fuel gas recovery scenario. …”

Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems by Shazia Bibi (16500318)

“…The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …”

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature by Maha Sellami (4351159)

“…Short-term (i.e., 10-24 weeks) moderate- to high-intensity strength training reduced LPS–IL-6, LPS, IL-1β, LPS–TNF-α and circulating concentrations of TNF-α and increased IL-10 in healthy elderly women and older people with cognitive impairment, respectively. …”

Optimization of Community Integrated Energy System for the State of Qatar Towards Sustainable Development by Abdelrahman Mahmoud Ahmed Moursi (22674269)

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study by Elkhansa Elbashier (14152815)

“…<p dir="ltr">Density functional theory is used to study the adsorption of natural gas components in calcite (10.4) cylindrical nanopores with 1–4 nm diameters. The change of adsorption energy with the diameter of the nanopores is studied for CH₄ and CO₂ gases. …”

Simulation of microscale particle interactions for optimization of an electrodynamic dust shield to clean desert dust from solar panels by Jennifer K.W. Chesnutt (18891895)

“…Dust transport distance per 10 cycles generally decreased as cycle frequency increased from 0.5 to 10Hz; however, transport distance per time was largest with an intermediate frequency of 1Hz. …”

The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells by Ibraheem M. Attafi (14151735)

“…Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. The toxic effects of Pb on the lung was associated with significant increases in NF-κB and AhR levels which was accompanied with increases in downstream targets genes, iNOS and CYP1A1, respectively. …”

The Effects of Spirulina Supplementation on Cardiometabolic Risk Factors: A Narrative Review by Sara Sokary (17337724)

“…<p dir="ltr">Spirulina (<i>Arthrospira platensis</i>) is a cyanobacterium associated with multiple health benefits. …”

Engineering the Surface and Mechanical Properties of Water Desalination Membranes Using Ultralong Carbon Nanotubes by Yehia M. Manawi (18091207)

“…More pronounced effect on membrane’s mechanical properties was observed due to compatibility of CNTs with PS matrix when compared to other factors (i.e., changes in the CNT aspect ratio). The water contact angle for PS membranes incorporated with commercial CNT sharply decreased from 73° to 53° (membrane hydrophilization) for membranes with 0.1 and 1.0 wt. % of CNTs, while for the same loading of produced CNTs the water contact angles for the membrane samples increased from 66° to 72°. …”

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar by Dina Abushanab (10696501)

“…Antimicrobials use and resource utilization, and their associated costs, declined after the maturity of ASP (i.e. positive cost saving), with a cost saving of QAR 458 (US$ 125) per 100-patient beds per year, signifying a benefit of QAR 458 generated for each QAR 1 invested in the ASP service. …”