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Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death
Published 2024“…Inhibition of autophagy decreased sensitivity to arginase-induced cytotoxicity in all cell lines, and hence reversed cell death. …”
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Secrecy Performance of a RIS-Assisted Wireless Network: A Comprehensive Analysis Under Outdated CSI
Published 2025“…To this end, the secrecy outage probability (SOP) metric is derived under the presence of outdated CSI (aging) at the RIS controller, considering four scenarios based on the availability of direct links between the transmitter and both receivers (i.e., the legitimate one and the eavesdropper). …”
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
Published 2010“…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …”
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Role of intravitreal antivascular endothelial growth factor injections for choroidal neovascularization due to choroidal osteoma
Published 2014“…By paired comparison, mean decrease from baseline was 119.7 microns at 6 months (n = 15; P = 0.001 ), 105.3 microns at 1 year (n = 10; P = 0.03 ), and 157.6 microns at 2 years (n = 7;p = 0.08 ). …”
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Bevacizumab and neovascular age related macular degeneration
Published 2011“…The mean number of letters gained, decrease in CRT, and number of injections were 8 letters, 125.3 µm, and 4.3 injections, respectively. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…Additionally, self-expandable valves were associated with a higher decrease in gradient than balloon ones (beta = 0.38; 95% CI [0.12–0.64]). …”
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Rescue cerclage
Published 2006“…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”
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Hydroxyurea Use in Lebanese Patients With [beta]-Thalassemia Intermedia
Published 2006“…Seven patients with [beta]-thalassemia intermedia received oral HU (10-20 mg/kg/d); the mean duration of therapy was 17.4 (range 6-46) months. …”
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
Published 2019“…Addition of excess L-citrulline rescued only one of three cell lines tested, indicating that the majority of cell lines are completely auxotrophic for arginine. …”
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Recent advances in the treatment and outcome of locally advanced rectal cancer
Published 1999“…Of those receiving any pre- or postoperative chemotherapy, three patients received chemotherapy in the early era, compared with 76 in the late era. …”
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Empiric antibiotic therapy of community-acquired Pneumonia at the American University of Beirut Medical Center. (c2001)
Published 2001“…Special attention should be given to decrease hospitalization rate, to preserve fluoroquinolones, and to improve microbiological studies outcome.…”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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Percutaneous Aspiration Irrigation Drainage Technique in the Management of Septic Arthritis in Children
Published 2011“…Result: Apyrexia was obtained after a mean period of 2 days. The mean draining duration was 4.5 days. …”
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
Published 2023“…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …”
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Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries
Published 2023“…The results indicate that non-oil real GDP exhibits an adverse and magnified response to an increase in remittance outflows, relative to a decrease. Furthermore, this negative impact is amplified when accounting for oil price changes. …”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…Following treatment of the hyperthyroidism, control was improved in 63%, with an 11-83% (mean 44%) decrease in insulin dosage in 59% of them. …”
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